Citric Acid Cycle Self Test

Description

Self test for Exam 2 Citric Acid Cycle first two pages.
Emily Richards
Quiz by Emily Richards, updated more than 1 year ago
Emily Richards
Created by Emily Richards over 3 years ago
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Resource summary

Question 1

Question
The citric acid cycle is an example of an amphibolic pathway.
Answer
  • True
  • False

Question 2

Question
The molecule shown is:
Answer
  • Biotin
  • Coenzyme A
  • Acetyl-CoA
  • Flavin mononucleotide
  • Lipoamide

Question 3

Question
The molecule shown above is a cofactor of:
Answer
  • succinate dehydrogenase
  • citrate synthase
  • alpha-ketoglutarate dehydrogenase
  • succinyl-CoA synthetase
  • pyruvate carboxylase

Question 4

Question
Which one of the following enzymes of the citric acid cycle catalyzes an irreversible step?
Answer
  • isocitrate dehydrogenase
  • succinate dehydrogenase
  • succinyl-CoA synthetase
  • fumarase
  • malate dehydrogenase

Question 5

Question
Which of the following conditions decreases the rate of oxidation of acetyl-CoA by the citric acid cycle?
Answer
  • a low ATP/ADP ratio
  • a low NAD+/NADH ratio
  • a low GTP/GDP ratio
  • a high NAD+/NADH ratio
  • an increase in Ca2+ concentration

Question 6

Question
In eukaryotes the enzymes of the citric acid cycle are found in the cytosol.
Answer
  • True
  • False

Question 7

Question
The citric acid cycle is an anaerobic pathway.
Answer
  • True
  • False

Question 8

Question
The only reaction in the citric acid cycle that produces a carbon-carbon bond is catalyzed by citrate synthase.
Answer
  • True
  • False

Question 9

Question
Which enzyme is unique to the glyoxylate cycle?
Answer
  • malic enzyme
  • malate dehydrogenase
  • isocitrate lyase
  • PEP carboxylase
  • pyruvate carboxylase

Question 10

Question
The only reaction of the citric acid cycle that provides substrate level phosphorylation is catalyzed by:
Answer
  • pyruvate dehydrogenase
  • malate dehydrogenase
  • isocitrate dehydrogenase
  • succinate dehydrogenase
  • succinyl-CoA synthetase

Question 11

Question
The molecule shown is:
Answer
  • biotin
  • coenzyme A
  • FAD
  • flavin mononucleotide
  • lipoamide

Question 12

Question
The molecule shown above is a cofactor of:
Answer
  • succinate dehydrogenase
  • citrate synthase
  • isocitrate dehydrogenase
  • succinyl-CoA synthetase
  • pyruvate carboxylase

Question 13

Question
Which one of the following enzymes of the citric acid cycle catalyzes an irreversible step?
Answer
  • succinyl-CoA synthetase
  • succinate dehydrogenase
  • citrate synthase
  • fumarase
  • malate dehydrogenase

Question 14

Question
In mammalian tissues, isocitrate dehydrogenase is allosterically stimulated by
Answer
  • high ATP/ADP ratio
  • low NAD+/NADH ratio
  • low acetyl CoA/CoA ratio
  • high NAD+/NADH ratio
  • a decrease in Ca2+ concentration

Question 15

Question
In eukaryotes the enzymes of the citric acid cycle are found in the mitochondria.
Answer
  • True
  • False

Question 16

Question
The citric acid cycle is an anaerobic pathway.
Answer
  • True
  • False

Question 17

Question
The only reaction in the citric acid cycle that produces substrate level phosphorylation is catalyzed by citrate synthase.
Answer
  • True
  • False

Question 18

Question
All of the statements below about the glyoxylate pathway are true EXCEPT:
Answer
  • The enzymes of the glyoxylate pathway are found in the glyoxysomes.
  • The glyoxysomes contain all of the enzymes of the citric acid cycle.
  • The glyoxylate pathway allows plants, yeast, and microorganisms to thrive using acetate as the sole carbon source.
  • The glyoxylate pathway bypasses the two oxidative decarboxylation reactions of the citric acid cycle.
  • In the glyoxylate pathway, isocitrate is routed through isocitrate lyase and malate synthase.

Question 19

Question
The anaplerotic reactions associated with the citric acid cycle are a result of:
Answer
  • The use of many of the citric acid cycle intermediates in biosynthesis.
  • The oxidative nature of the citric acid cycle.
  • The decarboxylation reactions of the citric acid cycle.
  • The production of reduced coenzymes.
  • The irreversible nature of three citric acid cycle reactions.
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