Question 1
Question
The most common manifestations in SLE are:
Answer
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A. Raynaud Phenomenon, involvement of gastrointestinal tract and lungs
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B. Vasculitis, blisters, involvement of kidneys
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C. Malar rash, photosensitivity and hematologic disorder (anemia, leucopenia)
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D. Erythema nodosum, conjunctivitis
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E. Red, subcutaneous nodules, painful, warm and tender
Question 2
Question
1. Mark a primary lesion in urticaria:
Answer
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a. Vesicle
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b. Blister
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c. Papule
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d. Macule
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e. Hive
Question 3
Question
8. Mark systemic agents used in the therapy of psoriasis:
Answer
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a. Isotretinoin, Itraconazole
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b. Tazarotene, Dapsone
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c. Deksametazon, Hydrocortison
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d. Methotrexate, Ustekinumab
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e. Doxycycline, Arechin
Question 4
Question
Choose connective tissue disease that can be treated with ultraviolet radiation:
Question 5
Question
Granular deposits of IgA in the dermal papillae found in direct immunofluorescence assay are the hallmark of:
Question 6
Question
The most typical localization of yeast infections are not:
Answer
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a. Oral mucosa
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b. Body folds
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c. Nail plates
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d. Groins
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e. Nail folds
Question 7
Question
Nontreponemal serological tests are:
Answer
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a. VDRL, TPHA, FTA
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b. FTA-ABS, TPHA, RPR
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c. USR, VDRL, RPR
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d. VDRL, FTA, USR
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e. USR, TPHA, VDR
Question 8
Question
Match feature of morphea:
Answer
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a. Calcium deposits in subcutaneous tissue
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b. poikilodermia
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c. telangiectasia
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d. Rat bite necrosis on fingertips
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e. hypopigmented, sclerotic lesions localized usually on the trunk
Question 9
Question
Herxheimers reaction is a/an:
Answer
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a. Intolerance reaction due to doxycycline
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b. Allergy to cephalosporins
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c. Inflammatory reaction due to spirochetal infection treatment
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d. Anaphylactic shock after penicillin
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e. Intolerance reaction due to procaine
Question 10
Question
58. Ficosis is a:
Answer
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a. Bacterial infection typical for vets and fishermen
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b. Furunculosis in diabetic patients
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c. Severe infection in neonates
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d. Purulent infection of beard region in male patients
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e. Cellulitis
Question 11
Question
Which drug is NOT used in the treatment of psoriasis?
Answer
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a. Azathioprin
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b. Cyclosporin
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c. Adalimumab
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d. Methotrexate
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e. Etanercept
Question 12
Question
2. Drug of first line in syphilis of CNS
Question 13
Question
Most common food allergen in infants?
Answer
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a. cow milk
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b. soy
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c. goat milk
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d. hen egg
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e. wheat
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d. nuts
Question 14
Question
Actinic keratosis (solar keratosis) treatment:
Question 15
Question
11. Keratoderma of feet and hands:
Answer
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a. Only in women
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b. Immediately after birth
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c. Can be acquired during cancer
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d. Inherited only in an autosomal dominant manner
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e. Hyperhydrosis occurs (excessive sweating)
Question 16
Question
15. In which of the following ulcers are NOT present:
Answer
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a. Erythema nodosum
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b. Mycosis fungoides
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c. Chronic pyoderma
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d. Thrombophlebitis
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e. Basal cell carcinoma
Question 17
Question
1.Which of the following is not true?
Answer
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a) food allergy or a reaction to an insect bite or sting can lead to urticaria
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b) mechanical trauma can lead to urticaria
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c) antihistaminic drugs can often lead to urticaria
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d) nonsteroidal antiinflammatory drugs (NSAIDS) can often lead to urticaria
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e) antibiotics can lead to urticaria
Question 18
Question
2.Which of the following cannot be used for treatment of Lichen Planus?
Answer
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a) Acitretin
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b) UVB therapy
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c) corticosteroid creams
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d) Doxacyclinum
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e) PUVA therapy
Question 19
Question
4.Which of the following connective tissue disease does not have systemic manifestations:
Answer
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a) discoid lupus erythematosus
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b) subacute cutaneous lupus erythematosus
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c) acroscleroderma
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d) mixed connective tissue disease
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e) dermatomyositis
Question 20
Question
5."Biological false positive reaction" is when:
Answer
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a) VDRL (+), FTAiABS (+)
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b) TPI (+), WR (+)
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c) VDRL (+), TPI (+)f
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d) FTAiABS (-), VDRL (+)
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e) TPI (+), FTAiABS (i)
Question 21
Question
6.Mark the wrong sentence about "Herxheimer's reaction":
Answer
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a) the reaction can be dangerous in older patients with cardiovascular disease
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b) it is the reaction after admitting penicillin
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c) is a result of penicillin intolerance
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d) can be prevented by oral steroids
Question 22
Question
7.A 39 year old man has become concerned regarding a skin lesion on his chest which has recently become darker with irregular borders present. This lesion has enlarged from 1cm to 1.5 cm over the past three months. On physical examination he has a slightly raised, irregular pigmented brown to black lesion on the skin of his right upper chest. Which of the following is the most likely diagnosis?
Question 23
Question
8.A 72-year old man has noted a slowly enlarging nodule on his lower eyelid for the past 3 years. On physical examination this lesion is a 0,7 cm firm mass with a pearly appearance and central umbilication. The lesion is excised, the margins of the excision are clear, and it does recur. Which of the following is the most likely diagnosis?
Answer
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a) Basal cell carcinoma
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b) Dermatofibroma
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c) Melanoma
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d) Neurofibroma
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e) Sebaceous carcinoma
Question 24
Question
9.Over the past 4 months a 25-year-old woman has noted the appearance of a skin rash on her face when she spends more than an hour in the sun. On physical examination there is an erythematous malar skin rash. Laboratory studies show a positive antinuclear antibody (ANA) test with a titer of 1:256 and anti-double stranded DNA titer of 1:256. A punch biopsy of non- sun exposed skin is performed. Immunofluorescence staining on this normal skin reveals band- like deposition of IgG and C3 at the dermal-epidermal junction. Which of the following immunologic disorders is she most likely to have?
Answer
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a) Polymyositsidermatomyosits
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b) Discoid lupus erythematosus (DLE)
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c) Systemic sclerosis (SS)
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d) Systemic Lupus Erythematosus (SLE)
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e) Graf versus host disease (GVHD)
Question 25
Question
10. A 55 year old man comes to his physician because of a rapidly enlarging nodule on his face. On physical examination there is a 1 cm diameter dome shaped, nesh coloured nodule on his right cheek. While waiting 3 months for a referral to a dermatologist in his managed health care plan,the lesion disappears. Which of the following is the most probable diagnosis:
Answer
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a) Skin tag
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b) Keratoacanthoma
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c) Dermatofibroma
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d) Bowen Disease
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e) Basal cell cancer
Question 26
Question
11. An 83 year old man comes to his physician for a routine check of his health status. On physical examination he has multiple 0.3 to 1.4 cm coinilike, lightly pigmented, velvety surface lesions on his face and upper chest. These lesions have been present for many years and slowly enlarging. They are not painful and do not bleed when rubbed. Which of the following is the most likely diagnosis for this mans skin lesions?
Question 27
Question
12.Which one of the following can develop into mycosis fungoides?
Question 28
Question
13.A 16 year old patient manifests: Dry skin, itching red to brownish gray patches, especially on the hands, feet, ankles, wrists, neck, upper chest, eyelids, inside the bend of the elbows and knees.Thickened, cracked, scaly skin and raw, sensitive, swollen skin from scratching can be seen. Mark the most probable diagnosis:
Answer
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a) Atopic dermatitis
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b) Scabies
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c) Mycosis fungoides
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d) SLE
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e) Psoriasis
Question 29
Question
14.Tinea pedum interdigitalis is most frequently caused by:
Answer
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a) Trichophyton rubrum and Trichophyton mentagrophytes
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b) Trichophyton ectothrix
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c) Microsporum canis
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d) Candida albicans and Staph. aureus
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e) Streptococcus pyogenes
Question 30
Question
15.Which method is not used in treatment of Pemphigus?
Answer
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a) Cyclophosphamide (Endoxan) intravenously
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b) Topical steroids
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c) Disulone (Dapsone) orally
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d) UVB therapy
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e) Prednisonum (Encorton) orally
Question 31
Question
16.Which sentence is NOT true about erysipelas?
Answer
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a) it can be caused by strep. pyogenes
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b) it can be recurrent after the removal of lymph nodes due to breast cancer
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c) it can be treated by Cephalosporins orally
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d) it can be treated by methotrexate
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e) it can lead to elephantiasis
Question 32
Question
17.Which sentence is true?
Answer
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a) mycosis fungoides can be caused by candida albicans
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b) Koebner phenomenon is characteristic for psoriasis disease
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c) Alopeta areata can be treated by oral and topical antifungal drugs
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d) Mi2 antibodies are most characteristic for SLE
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e) Antihistaminic drugs can be used in treatment of vitiligo
Question 33
Question
18.Which of the following features are characteristic for Atopic Dermatitis:
Answer
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a) elevated levels of IgE antibodies are present in majority of cases
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b) it affects older patents most frequently
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c) it is always associated with asthma
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d) it is characterized by increased photosensitivity of the skin
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e) Type IV of immunological reaction is the basic mechanism in pathogenesis of AD
Question 34
Question
19. A 5 year old girl with two sharply defined areas of erythema and gray scales localized on the scalp, with hairs broken off 2-3mm from the skin surface. Which examination is the most helpful to put the right diagnosis:a) antinuclear antibodies
Question 35
Question
20.Sharply bordered, slowly peripherally spreading, itchy patch or plaque with ofen "active edge"(redder border with scales and pustules). The most possible diagnosis:
Question 36
Answer
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a) nuid filled lesions with single or multiple chambers
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b) liable to ulceration and scarring
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c) nat, circumscribed change in skin colour
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d) superficial loss of epidermal tissue
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e) highly pruritic, appear and disappear very quickly
Question 37
Question
22.A 6 year old boy with small, flesh colored papules with a central dell on his face, hands and genitalia. Identical lesions are present in his 4 year old sister. The most probable diagnosis is:
Question 38
Question
23.Lichen Planus is characterized by:
Question 39
Question
24.Which of the following is NOT a cutaneous manifestaton of Lyme disease?
Question 40
Question
25.The appearance of punctate bleeding spots when psoriasis scales are scraped off. The description concerns:
Answer
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a.) Kobner phenomenon
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b) Auspitz sign
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c) Candle sign
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d) Nicolsky sign
Question 41
Question
26.Which of the following is NOT a characteristic histopathological feature of psoriasis?
Question 42
Question
27.Mark the autoimmune blistering disorder manifesting as pruritic eruption, classically seen on the buttocks and the extensor surfaces of the arms and legs is often associated with a gluten sensitive enteropathy
Question 43
Question
29.Alopecia areata may be associated with:
Answer
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a) hashimoto disease
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b) psoriasis
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c) pemphigus vulgaris
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d) Bowen disease
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e) urticaria
Question 44
Question
30.Which diagnostic examination should be performed in a 10 year old child diagnosed with atopic dermatitis:
Question 45
Question
31.What is the Pathogenesis of Pemphigus vulgaris?
Answer
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a) IgG Ab against desmoglein
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b) IgG Ab against hemidesmosome components
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c) Autoimmune depositon of IgA at tps of dermal papillae
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d) Enzyme defect in tyrosinase
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e) IgA Ab against hemidesmosome components
Question 46
Question
32.The most common manifestations in systemic sclerosis are:
Answer
-
a) malar rush, photosensitvity and hematologic disorder (anemia, leucopenia)
-
b) Raynaud phenomenon, involvement of gastrointestinal tract and lungs
-
c) vasculits, blisters, involvement of kidneys
-
d) erythema nodosum, conjunctvits
-
e) red, subcutaneous nodules, painful, warm and tender
Question 47
Question
A 40yo female complains of redness of the cheeks with papules, pustules and dilated blood vessels (telangiectasias). The lesions has been present for few years. The patent does not recognise any factors associated with the lesions. Mark the most probable diagnosis likely has:
Answer
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a) Seborrheic dermatitis
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b) Acne vulgaris
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c) SLE
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d) Rosacea
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e) Atopic dermatitis
Question 48
Question
36.In patient with hard and thickened skin, Raynaud phenomenon, ulcers or loss of bulk from finger....and positve SCL-70 antibodies one can use the following treatment:
Question 49
Question
40.Which of the following is reported to be precancerous lesion:
Question 50
Question
41.Which antibodies can lead to neonatal lupus erythematosus:
Question 51
Question
42.Which symptoms of following diseases are observed in Sharp syndrome:
Answer
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a) Pemphigus and pemphigoid
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b) Psoriasis, psoriasis arthritis and rheumatoid arthritis
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c) Scleroderma, systemic lupus erythematosus and dermatomyositis
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d) Systemic lupus erythematosus and Sjogren syndrome
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e) Pyoderma gangrenosum and Crohn's disease
Question 52
Question
44. Which of the following diseases is treated with systemic steroids:
Question 53
Question
45.Mark true sentence about bacterial skin disease
Answer
-
a) Carbuncle is a chronic folliculitis
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b) Contagious impetigo is usually occurring in adults
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c) Ficosis is typical for young female patients
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d) Furuncle is characterized by a necrotic plug
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e) Folliculitis is usually caused by Candida albicans
Question 54
Question
Mark true sentence about erysipeloid
Answer
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A. It is a streptococcal infection
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B. It is usually located on lower extremities
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C. It is a zoogenic infection
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D. It manifests as golden
-
E. It should be treated With Topical Antibiotics
Question 55
Question
47. The 58y old homeless male patient manifests multiple ulcerations covered with overlaid crusts. Skin lesions are painful and are localized mainly on lower extremities. There is a slight fever and high laboratory parameters of inflammation. Symptoms appeared a week ago. One can diagnose:
Answer
-
a) Erysipelas
-
b) Ecthyma
-
c) Eczema
-
d) Borreliosis
-
e) Psoriasis
Question 56
Question
48. Which diagnostic examination is usually (+) in patients with discoid lupus erythematosus:
Answer
-
A. Prick-test
-
B. Anti nuclear antibodies
-
C. Tzanck smear
-
D. LBT from unchanged skin - Negative in burn - out lesions, normal skin
-
E. Lupus Band Test from changed skin
Question 57
Question
49.Which areas of the skin are commonly infected by Candida species?
Answer
-
a. Interdigital spaces
-
b. Trunk
-
c. Scalp
-
d. Body folds
-
e. Lower extremities
Question 58
Question
51.Which antibodies are most characteristic for dermatomyositis:
Answer
-
a. Ku
-
b. ssDNA
-
c. Mi-2
-
d. Scl70
-
e. Ro
Question 59
Question
52. Recommended first-line treatment for uncomplicated urogenital Chlamydia trachomatis infections is:
Answer
-
Doxycycline
-
Tinidazole
-
Acyclovir
-
Fluconazole
-
Hydrocortisone
Question 60
Question
53. “Sky chart” appearance is the feature of:
Answer
-
Herpes zoster
-
Herpes simplex
-
Molloscum contagiosum
-
Chickenpox
-
Hpv infection
Question 61
Question
54. In a routine diagnosis of a 25y old pregnant female one revealed a positive result of Complement fixation reaction (WR) and negative Fluorescent Treponemal Antibody Absorption test (FTA-ABS). Mark most probable diagnosis:
Question 62
Question
55.. What is the contraindication for oral use of tretinoin:
Answer
-
Anemia
-
Hypocholesterolemia
-
Hypercholesterolemia
-
Infection
-
Circulating sezary cells
Question 63
Question
58. Which mole should immediately be surgically removed:
Answer
-
Diameter greater than 6 mm, uniform pigmentation and borders, elevated surface
-
Diameter greater than 6 mm, regular border
-
Diameter greater than 6 mm, changing color, asymetric shape
-
Localized on the scalp
-
Inborn mole with hairs