Question 1
Question
aspiration of a cystic lesion in the roght lobe of the liver reveals grayish brown pasty material , with streaks of blood , resembling anchovy sauce , microscopic examination of this material reveals necrotic debris , but no neutrophils and no pus cells , which of the following is the most likely diagnosis ?
Answer
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hepatic amoebiasis
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echinococcosis
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pyogenic abscess
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solitary unilocular cyst
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cavernous hemangioma
Question 2
Question
the autopsy of a 40 year old woman reveals a subcapsular mass in the right hepatic lobe , the mass is partially encapsulated , lighter in colour and the adjacent liver parenchyma appear compressed , histologically , the lesion is composed of normal hepatocytes , but no arranged in a lobular architecture , with absent portal tracts and central venules , which of the following is the most important predisposing factor for this lesion ?
Question 3
Question
an 18 year old male patient present with elevated liver enzymes , he has negative viral markers , negative anti nuclear antibody and anti smooth muscle antibody with decrease in the serum level of ceruloplasmin , liver biopsy was done and reveals deposition of brownish pigments in the hepatocytes , the most likely diagnosis of the patient is ?
Question 4
Question
a liver biopsy shows drop out of hepatocytes at the limiting plate with rosette formation and bridging necrosis , cellular infiltration by plasma cells is detected in zone (1) , the patient is postive for anto smooth muscle antibody , what is most likely diagnosis ?
Question 5
Question
a 52 year old woman has experienced malaise that has worsened during the past year , now physical examination reveals mild scleral icterus , there is no ascites or splenomegaly , serology result are postive for IgG anti HCV and HCV-RNA and negative for anti HAV, HBs Ag , ANA and AMA , her condition remains stable for month , which of the following morphologic finding is most likely to be present is the patient liver ?
Answer
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concentric onion skin bile duct fibrosis
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copper deposition within hepatocytes
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granulomatous bile duct destruction
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massive hepatocellular necrosis
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microvesicular steatosis
Question 6
Question
54 year old farmer has a history of GIT bilharziasis he developed ascities , hepatomegaly , and splenomegaly with hematemesis what is most likely the diagnosis?
Answer
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ameobic liver abscess
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portal hypertension
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cholelithiasis
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leukemia
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chronic active hepatitis
Question 7
Question
a 62 year old male patient has a long history of gall bladder stones , one day he presents to the emergency room with acuter abdomen , lab investigation reveal high level of serum amylase wihch of the following might be the cause of acute abdomen ?
Answer
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acute amoebic liver abscess
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acute suppurative appendicitis
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acute haemorrhagic pancreatitis
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acute viral hepatitis
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poratal hypertension
Question 8
Question
a 73 year old woman has noticed a 10 kg weight loss in the past 3 months , she is becoming increasingly icteric and has constant vague epigastric pain , nausea , on physical examination , there is mild tenderness to palpation in the upper abdomen , lab findings include a total serum billirubin concentration of 10mg/dl ,which of the following condition involving the pancreas is most likely to be present ?
Question 9
Question
the pancreas of a 50 year old patient show extensive haemorrhage and fat necrosis , chalky white deposits are seen in the omentum , beside alcoholism , the most common etilogic factor associated with this condition is ?
Answer
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acute ischaemia
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bile stones
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drugs
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hyper lipoproteinemia
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infections
Question 10
Question
a fatty femmale presents with repeated billiary colic underwent cholecystectomy , the gross pathology revealed enlarged strawberry coloured inner wall of gall bladder with a whitish stone at neck of bladder , which of the following is the most likely etiology ?
Answer
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empyema
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porcelain gall bladder
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cholesterosis
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cholangiocarcinoma
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hydrops