Question 1
Question
Indicate in which of the shown organs develops a coagulative necrosis
Answer
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Brain
-
Kidney
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Myocardium
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Intestine
Question 2
Question
Indicate in which of the listed organs liquefactive necrosis occurs:
Answer
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Liver
-
Kidney
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Brain
-
Myocardium
Question 3
Question
The outcome of anemic brain attack may be:
Answer
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Cyst
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Pseudocyst
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Gliosis
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Scarring
Question 4
Question
Caseous necrosis is typical for:
Answer
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Specific inflammation
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TBC
-
Enzyme fat necrosis
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Chronic pyelonephritis
Question 5
Question
At autopsy in the temporal lobe of the brain is found a cyst with a diameter of 2cm, with smooth walls filled with a clear pale yellow liquid. Specify what it is:
Answer
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Abscess of the brain
-
Pseudocyst of the brain
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Tumor
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Encephalitis
Question 6
Question
Is formalin a suitable fixative for proof of neutral fat with Sudan 3?
Question 7
Question
Which stains are used for detection of amyloid?
Question 8
Question
The term "patognomonic change" means?
Answer
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Changes with unclear origin
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Paradoxal changes
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Sufficient for diagnosis changes
-
Diffuse inflammatory changes
Question 9
Question
It is recommended that the material for the biopsy should be taken:
Question 10
Question
Hyaline-drop Degeneration is:
Answer
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Celluar
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Extracellular
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Protein
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Carbohydrate
Question 11
Question
Brown induration of the lung is seen in:
Question 12
Answer
-
In Pompe disease accumulation cholesterol in the liver
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In von Gierke glycogen accumulates primarily in the myocardium
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Tay-Sacks disease is known as the amavrotic idioty
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in Gaucher disease is observed deposition of cerebrozides
Question 13
Answer
-
Apoptosis is programmed cell death, necrosis - end stage degenerative processes
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Apoptosis affects individual cells, necrosis - large areas
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Necrosis induces an inflammatory response, apoptosis does not lead to tissue reaction
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Apoptosis is a reversible process, and necrosis can be stopped
Question 14
Question
With regard to the completeness of the survey which is the number of biopsies needed to be taken in the course of a routine autopsy?
Question 15
Question
Optimal for routine biopsy survey are:
Answer
-
Tissue fragment with a size of 1cm, immersed in a double volume of fixative for 3 hours
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Tissue fragments with size 4cm - 20 times the volume of the retainer, for 8 hours
-
In freezing microtome regardless of the size of the tissue
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Tissue cubes with size 1cm at 20 times larger volume of container for 24 hours
Question 16
Question
Proof of lipids is done by:
Answer
-
Freezing microtom
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Paraffin method
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Alcohol fixation
-
Staining with Sudan 3
Question 17
Question
For proof of carbohydrates is appropriate to use:
Answer
-
Freeze microtom
-
Formalin fixation
-
Alcohol fixation
-
PAS staining
Question 18
Question
Frozen section serves for:
Question 19
Question
Specify the correct meaning of the terms:
Answer
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Livores - postmortem discoloration
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Algor mortis - Stiffness of muscles
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Rigor morits - cooling of the body
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Decay of body - Autolytic changes
Question 20
Question
Which of the listed cellular injuries are irreversible:
Answer
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Necrosis
-
Apoptosis
-
Fatty degeneration
-
Cellular edema
Question 21
Question
Which of the following deposits are expression of protein degeneration?
Answer
-
Caunsilman's bodies
-
Russel's bodies
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Mallory's bodies
-
Asteroid bodies
Question 22
Question
"Tiger" heart is diagnosed in view of:
Question 23
Question
Amyloid has the following characteristics:
Answer
-
Shines in polarized light in Tioflavin S
-
In Congorot shows no fluorescence
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Ultrastructurally has fibrillary structure
-
Shows metachromasia on Perls
Question 24
Question
The reaction with the Prussian blue is used for the detection of:
Answer
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Mealnin
-
Bilirubin
-
Hemosiderin
-
Calcium
Question 25
Answer
-
Uniform, transparent and colourless
-
Cellular degeneration product
-
Extracellular degeneration deposit
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Causes an inflammatory response at the site of deposition
Question 26
Question
Metachromasia is:
Answer
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Immunohistochemical reaction
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Expression of cellular atypia
-
Changes the primary colour of the stain depending on the chemical composition of the substance
-
Impregnative methodology for argyropfilic fibers
Question 27
Question
Which colours are used in the detection of amyloid?
Question 28
Question
Which of the listed terms are related to amyloid deposit?
Answer
-
Porfiric down
-
Sago Spleen
-
Big White Kidney
-
Flint Liver
Question 29
Question
Point the main histological types of necrosis:
Answer
-
Coagulative necrosis
-
a heart attack
-
Gangrene
-
Liquefactive necrosis
Question 30
Question
Mutilation means:
Answer
-
A form of biological mutation
-
Pendulum-like movement of the blood
-
Zonal hair loss
-
Selfamputacion of the phalanges
Question 31
Question
A complete resection of altered tissue is achieved with:
Answer
-
Incisive biopsy
-
Excisive biopsy
-
Aspiration biopsy
-
Puncture Biopsy
Question 32
Question
Specify the characteristic signs of mucoid edema
Answer
-
Positive staining for fibrin
-
The basic substance shows eosinophillia
-
Positive PAS reaction
-
the transverse strip of collagen
Question 33
Question
Hyaline-drop degeneration is:
Answer
-
Extracellular
-
Cellular
-
Protein
-
CARB
Question 34
Question
Indicate pathological processes and diseases in which develops widespread connective tissue hyalinosis
Answer
-
Rheumatoid arthritis
-
Rheumatism
-
In hypertensive disease
-
Atherosclerosis
Question 35
Answer
-
Android obesity can be seen in women
-
Gynoid obesity is of superior type
-
Dercum's disease is due to pluriglandular endocrinopathy
-
In Madelunga syndrome
Question 36
Question
Specify which pigments are related to hemoglobinogenic:
Answer
-
Hemosiderin
-
Melanin
-
Lipofuscin
-
Porphyrin
Question 37
Question
Which pigments are formed in the center of hematomas
Answer
-
Hemosiderin
-
Lipofuscin
-
Hemomelanin
-
Hematoidin
Question 38
Question
The mechanical jaundice is:
Answer
-
Holostatic
-
Posthepatic
-
Direct
-
Hemolytic
Question 39
Question
In mechanical jaundice
Answer
-
Indirect bilirubin in the blood revails
-
In urine urobilinogen is not found
-
In the urine is found bilirubin
-
Stools are hyperpigmented
Question 40
Question
The reactions for the Purssian blue is used for:
Answer
-
Tattoos
-
Proof of bilirubin
-
Proof of hemosiderin
-
in hemochromatosis
Question 41
Question
In hemolytic jaundice is found:
Answer
-
Indirect bilirubin in the blood prevails
-
In urine urobilinogen is found
-
In the urine is found bilirubin
-
Stools are hyperpigmented
Question 42
Question
Specify which pigments are deposited in Brown atrophy of the liver?
Answer
-
Melanin
-
Lipofuscin
-
Hemosiderin
-
Hematoidin
Question 43
Question
Specify the characteristic signs of hemosiderin
Answer
-
Does not contain iron
-
Contains iron
-
Located in living cells
-
Is found extracellularly
Question 44
Question
Specify which pigments are elevated in hemolytic jaundice
Answer
-
Ferritin
-
Hemosiderin
-
Direct bilirubin
-
Indirect bilirubin
Question 45
Question
Specify the conditions and diseases in which is seen distrophic/degenerative/calcification
Question 46
Question
Hyaline is deposited
Answer
-
In plasma incorporation into vessel wall
-
End of local inflammatory processes
-
Outcome of fibrinoid necrosis
-
Liquefactive Necrosis
Question 47
Question
Where is developing fatty degeneration of liver in hyperlipidemia by overconsumption:
Question 48
Question
Specify which pathological processes show calcium metastases:
Answer
-
Hypercalcemia
-
Necrosis
-
Hypervitaminosis A
-
Atherosclerosis
Question 49
Question
Specify the conditions in which there is hyperpigmentation of the skin
Answer
-
Addison's disease
-
Ephelides
-
Vitiligo
-
Nevus
Question 50
Question
Which of the listed terms are associated with Amyloidosis?
Answer
-
Porphiric Spleen
-
Sago spleen
-
Large white kidney
-
Flint Liver
Question 51
Question
Specify the characteristic macroscopic change of organs in Amyloidosis
Question 52
Question
For amyloidosis is not characteristic one of the following qualitie
Question 53
Question
Point two possible outcomes of hydropic degeneration
Question 54
Question
Which of the listed cellular injuries are irreversible
Answer
-
Necrosis
-
Apoptosis
-
Balloon degeneration
-
Necrobiosis
Question 55
Question
Hemolytic jaundice may be:
Answer
-
Subhepatic
-
Prehepatic
-
Indirect
-
Obstructive
Question 56
Question
Which of the following is not a form of Amyloidosis
Answer
-
Primary
-
Reactive
-
Parenchymal
-
Local
Question 57
Question
In which diseases often develop Amyloidosis
Answer
-
Bronchiectatic disease
-
Malignant myeloma
-
Arterial hypertension
-
Rheumatoid artritis
Question 58
Question
Bilateral eyelid skin of adult shows nodules with yellow colour and rice grains, they are:
Answer
-
Xanthelasmi
-
Nevus pigmentosus
-
Ephelides
-
Hemosiderin deposits
Question 59
Question
In which diseases calcium deposits are called dystrophic?
Answer
-
At athercalcinosis
-
In the arterioles of the kidney
-
Psammoma type of meningeoma
-
In the heart valve defect
Question 60
Question
The comparison "signet ring cell" with a stone facing inwards is used in:
Answer
-
In fatty degeneration of hepatocytes
-
Mucus-producing adenocarcinoma
-
Vacuolar degeneration of hepatocytes
-
Henle's loop epithelial cells degeneration
Question 61
Question
Specify the typical deposition of amyloid for primary amyloidosis:
Question 62
Question
In the stomach is found a large tumor with mucus collection. Microscopically in the tumor slides are detected tumor cells with a doughnut shape which cytoplasm show PAS-positive stain. What type of degeneration is depicted in this case?
Question 63
Question
Indicate which of the following conditions is an example of local hemosiderosis:
Answer
-
Hemolytic anemia
-
Brown lung induration
-
Brown atrophy of liver
-
Lipogranulom
Question 64
Question
Specify enzymes involved in melanogenesis
Answer
-
Hyaluronidase
-
Tirozinaza
-
DOPA-oxidase
-
Lipase
Question 65
Question
The sequence of local structural changes in the course of the disease is called
Answer
-
Sanogenesis
-
Pathogenesis
-
Tanathogenesis
-
Morphogenesis
Question 66
Question
The mechanical jaundice is:
Answer
-
Indirect
-
Posthepatic
-
Direct
-
Hemolytic
Question 67
Question
Hyaline is deposited in
Question 68
Question
Specify the conditions under which does not develop fatty degeneration of the liver:
Answer
-
Active hyperemia
-
Chronic pulmonary heart
-
Anemia
-
Diabetes mellitus
Question 69
Question
Which of the following is not a form of amyloidosis
Answer
-
Primary
-
Reactive
-
Into paraenchymal cells
-
Local