Zusammenfassung der Ressource
Adaptive Immunity (ONLY Lecture 15
Part 2)
- Humoral Immunity
- "Antibody-mediated"
- B-cell based
- Cellular Immunity
- "Cell-mediated"
- T-cell based
- Types
- Naturally acquired active
- Getting sick
- B memory cells
- Nat. acq. passive
- Transfer
(mother's milk)
- Artificially acq. active
- Vaccination
- Art. acq. passive
- Antibodies from
one host intro to
another
- Antigens
- Epitopes
- Reaction sites
on antigens for
specific antibody
or T cell receptor
- Affinity
- Binding
strength at just
ONE site
- Avidity
- Overall
antigen-binding
at ALL sites
- Major Histocompatibility
Complex (MHC)
- Genes
code for
self/nonself
- In humans "Human
Leukocyte Antigen"
(HLA)
- Three Classes
- CLASS I
- All types
- Important for
organ transplant
- CLASS II
- Antigen-presenting
cells
- Important for T-cell
communications
- Macrophages
- Dendritic cells
- B cells
- CLASS III
- Secreted
proteins
- Nonself/self
recognition
- Class I and II
Structures
- Heterodimers
of alpha &
beta subunits