1795769
Beschreibung
Mindmap von vaish_rai28, aktualisiert more than 1 year ago
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Erstellt von vaish_rai28
vor fast 10 Jahre
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CHIKUNGUNYA
- CAUSATIVE AGENT
- virus : alphavirus from togaviridae family
- vector : Aedes aegyptii mosquito ; no animal reservoir
- Cycle of infection : Man- Mosquito-Man ; Incubation period: 2 to 12 days
- virus : alphavirus from togaviridae family
- HISTORY
- First isolated from human patients from Tanzania in 1952
- first appeared in India in 1963
- First isolated from human patients from Tanzania in 1952
- SYNONYMS
- CHIK Fever; Buggy creek virus infection; Knuckle fever, Me Trivirus infection,
Semliki Forest virus infection
- CHIK Fever; Buggy creek virus infection; Knuckle fever, Me Trivirus infection,
Semliki Forest virus infection
- SYMPTOMS
- Sudden onset of fever, chills, Lymphadenopathy, Headache, Nausea, Abdominal pain, Joint pain, Low back pain & Rash
- Sudden onset of fever, chills, Lymphadenopathy, Headache, Nausea, Abdominal pain, Joint pain, Low back pain & Rash
- CLINICAL FEATURES
- Viremia for 5 days; Biphasic fever with remisssion after 6 days; high grade fever; Arthralgia lasting several weeks
- Viremia for 5 days; Biphasic fever with remisssion after 6 days; high grade fever; Arthralgia lasting several weeks
- LAB DIAGNOSIS
- 1)Four fold or more rise of HI Antibody 2) IgM capture ELISA using MAbs 3) Indirect Immuno Flourescence
Test (I IFT) On infected cells from tissues 4) Virus Isolation – Infant Swiss Albino mice Vero BHK-21 cell
lines are used 5) Nucleic acid amplification by PCR & RT PCR
- 1)Four fold or more rise of HI Antibody 2) IgM capture ELISA using MAbs 3) Indirect Immuno Flourescence
Test (I IFT) On infected cells from tissues 4) Virus Isolation – Infant Swiss Albino mice Vero BHK-21 cell
lines are used 5) Nucleic acid amplification by PCR & RT PCR
- TREATMENT
- 1)Rest to the patient and mild movements of joints 2)Cold compresses to inflamed joints 3) Liberal fluid
intake or IV fluids Analgesics and NSAIDS Paraetamol ± Ibuprofen or aceclofenac or diclofenac
Naproxen sodium (Naprasyn, Xenobid) Aspirin should be avoided Hydroxy chloroquine sulphate
(HCQS) 200 mg/od Chloroquine phosphate 250 mg/od
- 1)Rest to the patient and mild movements of joints 2)Cold compresses to inflamed joints 3) Liberal fluid
intake or IV fluids Analgesics and NSAIDS Paraetamol ± Ibuprofen or aceclofenac or diclofenac
Naproxen sodium (Naprasyn, Xenobid) Aspirin should be avoided Hydroxy chloroquine sulphate
(HCQS) 200 mg/od Chloroquine phosphate 250 mg/od
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