Heart Myocytes

Beschreibung

An example of a Direct- Effector Linked Pathway in Heart Myocytes. Note: The same neurotransmitter (acetylcholine) causes the opposite effect in skeletal muscle.
Sophie Barrett
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Sophie Barrett
Erstellt von Sophie Barrett vor fast 11 Jahre
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Zusammenfassung der Ressource

Heart Myocytes
  1. Stimulation from parasympathetic nervous system
    1. Acetylcholine acts on metabotropic, muscarinic receptors in the heart
      1. G-Protein is activated
        1. Effector protein is a K+ ion channel (stimulated to open)
          1. K+ ions flow out of the cell (down their concentration gradient)
            1. Increases negativity inside the cell (hyperpolarisation)
              1. Leads to decreased contraction
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