Genes, Alleles, & The Central Dogma

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First year Genetics & Society (Genes, Alleles, and the Central Dogma) Mindmap am Genes, Alleles, & The Central Dogma, erstellt von clairegillian95 am 03/04/2014.
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Genes, Alleles, & The Central Dogma
  1. Transcription occurs in the nucleus of the cell. (DNA -> mRNA)
    1. Translation occurs in the cytoplasm of the cell. (mRNA -> protein)
      1. Structural Gene
        1. Regulatory Region
          1. Determines when and how often transcription occurs
            1. Transcription factors bind
            2. Protein-encoding Region
              1. Specifies the amino acid sequence of the protein
              2. RNA polymerase binds to a special DNA sequence called the promoter
              3. DNA
                1. The basic unit of DNA is the nucleotide
                  1. A nucleotide consists of a phosphate, sugar, & nitrogenous base
                    1. Sugar
                      1. Deoxyribose in DNA
                        1. Ribose in RNA
                        2. Nitrogenous Bases
                          1. Adenine, Thymine, Guanine, & Cytosine; Uracil instead of Thymine in RNA
                    2. Post-translational modification of proteins
                      1. Folding, addition of sugars and/or lipids, shortening, linking to other proteins
                      2. Protein Targeting
                        1. A short amino acid sequence in the protein (signal sequence) directs the protein to various locations in the cell
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