Disorders of the Neuromuscular Junction & Muscle

Beschreibung

Disorders of the Neuromuscular Junction & Muscle given on 26/09/2018
Matthew Coulson
Quiz von Matthew Coulson, aktualisiert more than 1 year ago
Matthew Coulson
Erstellt von Matthew Coulson vor etwa 6 Jahre
145
1

Zusammenfassung der Ressource

Frage 1

Frage
Lambert Eaton Myasthenic Syndrome is a autoimmune disease whereby antibodies attack and destroy ...
Antworten
  • Presynaptic Vesicles
  • Presynaptic Calcium Channels
  • Postsynaptic Receptors

Frage 2

Frage
Lambert Eaton Myasthenic Syndrome typically causes muscle weakness in which parts of the body?
Antworten
  • Distal limbs (arms and legs)
  • Proximal limbs (arms and legs)
  • Typically legs only
  • Typically arms only

Frage 3

Frage
60% of patients with Lambert-Eaton Myasthenic Syndrome have an underlying malignancy. Which malignancy does it most commonly present with?
Antworten
  • Small cell lung cancer
  • Adenocarcinoma of the lung
  • Squamous cell lung cancer
  • Large cell lung cancer
  • Breast cancer
  • Renal cancer

Frage 4

Frage
What is the most common disorder of the neuromuscular junction?
Antworten
  • Lambert-Eaton Myasthenic Syndrome
  • Myasthenia Gravis
  • Neuromyotonia
  • Congenital Myasthenia

Frage 5

Frage
Myasthenia Gravis is an autoimmune condition whereby the body develops autoantibodies against [blank_start]acetylcholine[blank_end] receptors
Antworten
  • acetylcholine

Frage 6

Frage
Symptoms of Myasthenia Gravis only tend to start once ACh receptors are reduced to [blank_start]30[blank_end]% of normal
Antworten
  • 30
  • 60
  • 5

Frage 7

Frage
Which of the following structures is also known to play a part in Myasthenia Gravis?
Antworten
  • Thymus
  • Bone Marrow
  • Thalamus
  • Pituitary Gland
  • Adrenal Gland

Frage 8

Frage
Males tend to typically present with Myasthenia Gravis in their 30s whereas woman tend to present in their 60s-70s
Antworten
  • True
  • False

Frage 9

Frage
The difference between Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome is that ...
Antworten
  • Myasthenia Gravis tends to present mostly in the proximal legs, but not the arms.
  • Myasthenia Gravis tends to present mostly in the proximal arms, but not the legs.

Frage 10

Frage
Whilst Myasthenia Gravis typically presents with proximal weakness of the proximal leg muscles, it also tends to cause weakness in which of the following?
Antworten
  • Extraocular muscles
  • Facial muscles
  • Carpal muscles
  • Tarsal muscles
  • Abdominal muscles
  • Investing fascia muscles

Frage 11

Frage
The initial therapy for most patients with myasthenia gravis is an oral acetylcholinesterase inhibitor, usually [blank_start]pyridostigmine[blank_end]
Antworten
  • Pyridostigmine
  • Physostigmine
  • Neostigmine
  • Rivastigmine

Frage 12

Frage
Aminoglycoside antibiotics impair neuromuscular transmission and can cause clinically significant muscle weakness, resulting in respiratory depression in myasthenia gravis patients. Therefore, which of the following medications should be avoided in such patients?
Antworten
  • Gentamicin
  • Ceftriaxone
  • Amoxicillin
  • Metronidazole
  • Doxycycline

Frage 13

Frage
Inability to relax voluntary muscle after vigorous effort is known as [blank_start]myotonia[blank_end].
Antworten
  • myotonia

Frage 14

Frage
Rhabdomyolysis releases high amounts of [blank_start]Myoglobin[blank_end] into the plasma thus causing Acute Kidney Injury (AKI)
Antworten
  • Myoglobin
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