Pancytopenia

Assessment of Lymphadenopathy: Tender: Yes Consistency: Hard Surface: Smooth Skin inflammation?: No Tethered: No This describes a [blank_start]viral[blank_end] cause of lymphadenopathy Assessment of Lymphadenopathy: Tender: Yes Consistency: Hard Surface: Smooth Skin inflammation?: Yes Tethered: Maybe This describes a [blank_start]bacterial[blank_end] cause of lymphadenopathy Assessment of Lymphadenopathy: Tender: No Consistency: Rubbery/Soft Surface: Smooth Skin inflammation?: No Tethered: No This describes a [blank_start]lymphoma[blank_end] cause of lymphadenopathy Assessment of Lymphadenopathy: Tender: No Consistency: Hard Surface: Irregular Skin inflammation?: No Tethered: Yes This describes a [blank_start]metastatic carcinoma[blank_end] cause of lymphadenopathy

If lymphoma or other malignancy is expected in a lymph node, a [blank_start]core[blank_end] biopsy should be conducted

Lymphoma can be diagnosed by a CT Scan

Reed Sternberg Cells are diagnostic of which condition? [blank_start]Hodgkin's[blank_end] Disease

Recurrent nosebleeds and menorrhagia are associated with a defect in [blank_start]primary[blank_end] haemostasis

Pancytopenia is generally defined as a reduction of which three cells types in the blood?

Pancytopenia typically excludes lymphocytes

A clinical finding of pancytopenia is diagnostic of bone marrow failure

[blank_start]Fanconi's[blank_end] anaemia is an Inherited Bone Marrow Failure Syndrome, which typically presents in children around the age of 7 which clinical features such as short stature, skeletal abnormalities and cafe au lait spots.

[blank_start]Fanconi's[blank_end] Anaemia is an inability to correct inter-strand cross links (DNA damage)

The autoimmune condition whereby antibodies attack the haemopoietic stem cells of the bone marrow is called Idiopathic [blank_start]Aplastic[blank_end] Anaemia

Acute Myeloid Leukaemia typically causes pancytopenia

Which 3 of the following can cause Secondary Bone Marrow Failure?

[blank_start]Hypersplenism[blank_end] can cause pancytopenia due to an increased rate of cell destruction

Which three of the following can cause Hypersplenism?

Aplastic anaemia is a [blank_start]hypocellular[blank_end] condition