Clinical Immunology Test 2- PMU

Beschreibung

Medicine Immunology Quiz am Clinical Immunology Test 2- PMU, erstellt von Med Student am 11/04/2019.
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Quiz von Med Student , aktualisiert more than 1 year ago
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Erstellt von Med Student vor mehr als 5 Jahre
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5

Zusammenfassung der Ressource

Frage 1

Frage
The lymphoid inflitration of thyroidea is typical for
Antworten
  • Hashimoto's Thyroiditis
  • Euthroid struma
  • Hemolytic anemia
  • Tuberculosis

Frage 2

Frage
Which method is not useful for detection of specific IgE?
Antworten
  • imumonoenzyme techniques (ELISA. immuno blot)
  • classic reactions (agglutination, precipitation)
  • flowcytometry
  • chemiluminescence

Frage 3

Frage
I type allergic reactions are
Antworten
  • immuno-complex
  • cytotoxic
  • IgE mediated
  • cell mediated

Frage 4

Frage
Monoclonal antibodies connected with diphtheria toxin could be used for
Antworten
  • tumor diagnosis
  • immunostimulation
  • immunosuppressive therapy
  • immunotherapy for tumors

Frage 5

Frage
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics a. Multiple sclerosis [blank_start]6[blank_end] b. SLE [blank_start]4[blank_end] c. Myasthenia gravis [blank_start]5[blank_end] d. Pernicious anemia [blank_start]1[blank_end] e. Hashimoto thyoiditis [blank_start]2[blank_end] f. Hemolytic anemia [blank_start]3[blank_end] 1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12 2. autoantibodies against thyroglobuline and thyroid peroxidase 3. antibodies against epitopes of red blood cells 4. antibodies against nucleus antigens 5. antibodies against acetylcholine 6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
Antworten
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
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  • 1
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  • 5
  • 6
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  • 6
  • 1
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  • 6
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Frage 6

Frage
Which of the following human tumor antigens are connected with melanoma malignuum?
Antworten
  • CA 15-3
  • gp 1900
  • MART-1 Melan A
  • gp 120

Frage 7

Frage
Type II allergic reactions are realized through
Antworten
  • anaphylaxis
  • complement-mediated cytolysis
  • immune complexes
  • infectious immunity

Frage 8

Frage
EBV can cause development of
Antworten
  • hepatoma
  • nasopharyngeal carcinoma
  • the Burkitt lymphoma
  • adenocarcinoma pulmonis

Frage 9

Frage
Anaphylactic reactions
Antworten
  • are developed in very short time - 30 min
  • can be followed by inflammatory complication some hours later
  • are result of release of active mediators
  • all answers are correct

Frage 10

Frage
Autoimmune diseases due to antibodies could be a result of: (mark the wrong answer)
Antworten
  • generation of antigen-antibody complexes
  • antibody-induced complement mediated cytolysis
  • antibodies that inhibit cell receptor
  • cell-mediated reaction

Frage 11

Frage
The Bence-Jones protein can be find mostly in
Antworten
  • urine and serum
  • liquor
  • joint puncture
  • tumor biopsy

Frage 12

Frage
Immuno - scintigraphy uses monoclonal antibodies against tumor antigens connected with
Antworten
  • FITC
  • Rodamine
  • Iodine-131, technetium
  • Enzyme

Frage 13

Frage
What as it we can use as a substrate for detecting of antinuclear antibodies with IFA
Antworten
  • rat liver
  • rat kidney
  • rat stomach
  • HEp2 cell line

Frage 14

Frage
Point two diseases where we can use the Mantoux reaction [blank_start]Leprosy[blank_end] [blank_start]Tuberculosis[blank_end]
Antworten
  • Leprosy
  • Tuberculosis

Frage 15

Frage
CA-15-3 is a marker for first choice in diagnosis of:
Antworten
  • Hepatoma
  • Ca glandulae mamme
  • Melanoma malignum
  • Astrocytoma

Frage 16

Frage
III type allergic reaction is developed through
Antworten
  • SLE
  • Rheumatoid arthritis
  • Contact dermatitis
  • Acute rheumatism

Frage 17

Frage
The blocking factors secreted from tumor cells during tumor growth
Antworten
  • stop cell growth of tumor cells
  • stop the action of Tc-lymphocytes onto tumor cells
  • stop stimulation of tumor specific B-cells
  • are connected with T-lymphocytes and lead to lysis of tumor cells

Frage 18

Frage
Systemic lupus erythematodes
Antworten
  • is caused by mutation in dsDNA
  • is an example of T mediated disease
  • is manifested with many symptoms and affect many organs
  • is a result of forming of immune complexes

Frage 19

Frage
The atopic diseases are developed because:
Antworten
  • often contacts with allergen
  • they are inheritable
  • they are developed due to immune complexes
  • of IgE

Frage 20

Frage
We find autoantibodies against cytotoxic antigens of neutrophils (ANCA) mainly in
Antworten
  • the Goodpasture syndrome
  • amyloidodis
  • granulomatosis of Wegener
  • none of this

Frage 21

Frage
The Bence-Jones protein is
Antworten
  • free heavy chains
  • free light κ or λ chains, imperceptible with electrophoresis
  • autoantibodies from IgM class against normal antibodies (IgG) in patients with rheumatoid arthritis
  • fc fragment of complement

Frage 22

Frage
CEA is increased in
Antworten
  • nasopharyngeal carcinoma
  • lymphoma Burkitt
  • gastrointestinal tumors
  • smokers

Frage 23

Frage
The most used techniques for detection of antinuclear antibodies antibodies are
Antworten
  • direct immmunofluocrescent test
  • indirect immunofluorescent test
  • agglutination
  • neutralization
  • reaction for
  • ELISA

Frage 24

Frage
How fast is the reaction in cases of type 1 hypersensitivity?
Antworten
  • after 15-30 minutes
  • after 48 hours

Frage 25

Frage
The most frequent biological carcinogens are
Antworten
  • Mycoplasmas
  • Chlamydia
  • DNA- viruses
  • RNA- viruses

Frage 26

Frage
Connect with arrows allergic diseases with relevant type allergic reaction a. Type I [blank_start]3[blank_end] b. Type II [blank_start]4[blank_end] c. Type III [blank_start]1[blank_end] d. Type IV [blank_start]2[blank_end] 1. serum disease 2. contact dermatitis 3. anaphylaxis 4. hemolytic disease of the newborn
Antworten
  • 3
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Frage 27

Frage
Glomerutonephritis and vessel diseases due to antibodies are typical for
Antworten
  • the Arthus Phenomenon
  • edema angioneuroutic
  • SLE
  • anaemia haemolytica

Frage 28

Frage
Anti-mitochondrial antibodies are mostly
Antworten
  • detected in patients with primary biliary cirrhosis
  • detected in patients with rheumatoid arthritis
  • do not harm the organism

Frage 29

Frage
In case of Ca glandulae prostate is increased the serum levels of
Antworten
  • PSA (prostate specific antigen)
  • Antibodies against H.pylori
  • Calcitonin
  • Progesterone

Frage 30

Frage
Auto antibodies against microsomes of thyroid cells can be detected in case of
Antworten
  • Ca gl. thyroidae
  • Ca renis
  • Pancreatitis
  • Ca pancrei

Frage 31

Frage
Autoimmune hemolytic anemia in developed mostly via
Antworten
  • Type I allergic reactions
  • Type II allergic reactions
  • Type III allergic reactions
  • Type IV allergic reactions

Frage 32

Frage
Rheumatoid factor from the serum of patients with rheumatoid arthritis is
Antworten
  • IgM reacting with Fc fragment of endogenous IgG
  • IgM reacting wit Fab fragment of IgG
  • IgE reacting with bacterial antigens
  • Acute-phase proteins
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