Frage 1
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Which of the following methods is suitable for detectin of serum globulins?
Frage 2
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Type II allergic reations are realized by
Frage 3
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Monoclonal antibodies are
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pure population of immunoglobulins with same structure ant antigen specifity
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albumins that are coded from other group of genes
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mixed population of immunoglobulins with same structure, but different antigen specifity
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substrate causing expression of immunoglobulins from other class in B-cells
Frage 4
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Which immunological method is not proper for detecting of specific IgE
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Immuno-enzyme(ELİSA, immuno-blot technique)
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Classical ones(agglutination, precuipitation)
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Floucytometry
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Chemilluminescence
Frage 5
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Low levels of IgA are found in case of
Frage 6
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Auto immune disease due to antibodies could be a result of (point the wrong answer)
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forming of antigen-antibody complexes
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antibodies that blockade cell receptor
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antibody-depended cell-mediated cytotocicitty(ADCC)
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cell-mediated reaction
Frage 7
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The name of resident macrophages in liver is
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ostephages
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lagerhance cells
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kupfer cells
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microglial
Frage 8
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Hepatoma
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Nasopharyngeal carcinoma
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Burkit lymphoma
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Adenocaqrcinoma pulmonis
Frage 9
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Which of the following indicators is the most important in case of detecting of immune status in AIDS
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The bence-jones protein
Frage 10
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System lupus erythematosus
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is caused by mutations in ds-DNA
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is revealed with many symptoms and affects many organs
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is an example of T-cell mediated disease
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is a result of generating of immune complexes
Frage 11
Frage
The opsonisation is a process of
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Ingestion and destruction of an antigen from phagocyte
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Of covering of antigen with antibodies in purpose to ease phagocytosis
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Of covering of antigen with complement in purpose to ease phagoytosis
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Obtaining of monoclonal antibodies
Frage 12
Frage
Connect with arrows allergic diseases with relevant types allergic reactions:
Type [blank_start]3[blank_end] - serum-disease
Type [blank_start]4[blank_end] - contact dermatitis
Type [blank_start]1[blank_end] - anaphylaxis
Type [blank_start]2[blank_end]- hemolytic disease of newborn
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3
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Frage 13
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The mature B-lymphocytes expresses onto their surface
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IgM and IgD
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IgM and IgA
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IgD and IgE
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IgG and IgD
Frage 14
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The lymphocyte infiltration of thyroidea is typical for
Frage 15
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The electrophoresis is
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radial immunodiffusion in gel
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separation of molecules in electric field
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complement fixation reaction
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electroimmunodiffusion
Frage 16
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I type allergic reactions are
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Immunocomplex
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Cytotoxic
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IgE mediated
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Cell mediated
Frage 17
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Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics
a. Multiple sclerosis [blank_start]6[blank_end]
b. SLE [blank_start]4[blank_end]
c. Myasthenia gravis [blank_start]5[blank_end]
d. Pernicious anemia [blank_start]1[blank_end]
e. Hashimoto thyoiditis [blank_start]2[blank_end]
f. Hemolytic anemia [blank_start]3[blank_end]
1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12
2. autoantibodies against thyroglobuline and thyroid peroxidase
3. antibodies against epitopes of red blood cells
4. antibodies against nucleus antigens
5. antibodies against acetylcholine
6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
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6
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Frage 18
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The monoclonal antibodies, connected with diphtheria toxin could be used for
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tumour diagnosis
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immunostimulation
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immunosupperession
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immunotherapy of tumors
Frage 19
Frage 20
Frage
What is the mechanism of III type allergic reactions
Frage 21
Frage
Which of the following tumour markers are connected with melanoma maligna?
Antworten
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CA-15-3
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gp 120
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S100B
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MART-1Melan A
Frage 22
Frage
Immuno-scintigraphy uses monoclonal antibodies against tumour antigen connected with
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FITC
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Rhodamine
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Iodine 131, technetium
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Enzyme
Frage 23
Frage
INF-γ is produced by
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Activated T lymphocytes
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Fibroblasts
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B-lymphocytes
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Leucocytes
Frage 24
Frage
What kind of auto-antibodies we find in patients with insulin-depended sugar diabetes?
Antworten
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Nucleus
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Thyroid microsomes
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IgG molecules
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Island cells of pancreas
Frage 25
Frage
Rejection of a transplantant due to pre-forming antibodies in recipient is defined as
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Hyper acute rejection
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Accelerated
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Acute
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Chronic
Frage 26
Frage
What of the following possesses the most expressed oncogenic potential
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Influenza virus type A
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Ebola virus
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EBV
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Polioviruses 1,2 ,3
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HPV
Frage 27
Frage
Is the following correct?
Active immunity is a nospecific and is an ancient form of defense and lower degree of effectiveness?
Frage 28
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Type IV allergic reactions are realized by means of
Frage 29
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True hypersensitivity reactions start usually after
Frage 30
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Which of the following characteristics does not belong to the Burkit lymphoma?
Frage 31
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Antigen presenting cells are
Frage 32
Frage
We could use the mantoux test in diagnosis of (point two diseases)
a- [blank_start]Tuberculosis[blank_end]
b- [blank_start]Leprosy[blank_end]
Frage 33
Frage
Which of the following factors belong to the innate immunity?
Antworten
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Phagocytosis
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T-lymphocytes
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Complement, mucin, a-and b inferferons
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Antibodies
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Skin, mucus, normal flora
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B-lymphocytes
Frage 34
Frage
What we could use as a subsrrate for detection of antinuclear antibodies throguh IFA?
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rat liver
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rat kidney
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rat stomach
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hep2 cell line
Frage 35
Frage
Which of the pointed immunological parameters is most important for detection of multiple myleoma?
Antworten
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Frage 36
Frage
The most popular techniques for detection of antinuclear antibodies are
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Agglutination
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Indirect immunofluorescence
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Neutralization test
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The complement fixation test
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ELISA
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Direct immunofluorescence
Frage 37
Frage
CD3 molecule is a marker for
Frage 38
Frage
The accelerated reaction for rejection of transplantant is revealed
Antworten
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Intra-operative or immediately after operation
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24-to 72 hours after transplantation
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Till the third month
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3 month after the transplantation
Frage 39
Frage
which of the following immunological indexes ids the most important for patients with chronic granulomatous disease?
Antworten
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NBT test
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Anti DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Frage 40
Frage
CEA is increased in case of
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nasopharyngeal carcinoma
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the Burkit lymphoma
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gatro-intestinal tumors
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smokers
Frage 41
Frage
Which of the following is connected with damage of humoral immunity?
Frage 42
Frage
How many are complement activating ways?
Frage 43
Frage
The complement activation occurs via three pathways which are:
1. [blank_start]Classical[blank_end] pathway
2. [blank_start]Alternative[blank_end] pathway
3. [blank_start]Lectin[blank_end] pathway
Antworten
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Classical
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Alternative
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Lectin
Frage 44
Frage
The “respiratory burst" is related to
Antworten
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Humoral immunity
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Cellular immunity
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Phagocytosis
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NK-cells function
Frage 45
Frage
The immune competence of T-lymphocytes is acquired in
Antworten
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Thyroidea
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Bone marrow
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Thymus
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MALT
Frage 46
Frage
What expresses the CD8 molecule?
Antworten
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Macrophages
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Antigen presenting cells
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Cytotoxic T-lymphocytes
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T- suppressors
Frage 47
Frage
What is human cell receptor for human immunodeficiency virus (HIV)?
Antworten
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CD3 molecule
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CD8 molecule
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CD4 molecule
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CD19 molecule
Frage 48
Frage
Point the WRONG answer:
Gamma interteron is produced by:
Antworten
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Non-activated macrophages and mastocytes
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Leucocytes and Fibroblasts
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Activated macrophages and NK cell
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Lymphocytes
Frage 49
Frage
The determination of functional activity of the complement might be done by
Frage 50
Frage
CD4 molecule is situated on the surface of the
Antworten
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Monocytes
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T-helpers
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Cytotoxic T-lymphocytes
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Plasmocytes
Frage 51
Frage
The presence of the antigen together with the MHC-II class molecules is realized by
Frage 52
Frage
A B-cell can synthesise some different antibodies with different species of the antigen
Frage 53
Frage
After the antigen stimulus the mature B-lymphocytes are transformed into
Antworten
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cytotoxic cell
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immunocompetent cell
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plasmocyte
Frage 54
Frage
What tests are for evaluation of the phagocytic activity?
Frage 55
Frage
Paraproteinemias are detected in
Frage 56
Frage
Last cells, incapable to divide are
Antworten
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Plasmocytes
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Neutrophils
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T-lymphocytes
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B-Iymphocytes
Frage 57
Frage
What do the mature B-lymphocytes express on their surface?
Antworten
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lgM and IgD
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IgD ant IgE
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IgM and IgA
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IgG and IgD
Frage 58
Frage
How do CD8 eliminate their targets?
Antworten
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after recognition of antigen, connected with MCH-I class molecule
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after recognition of antigen connected with MCH-II class molecule
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via activation of an alternative way of complement
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due releasing of interferon