412799
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor etwa 11 Jahre
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Frage 1
Frage
What is the main difference between apoptosis and necrosis?
Antworten
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In necrosis release of cell contents is controlled In apoptosis it's not
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In apoptosis release of cell contents is controlled In necrosis it's not
Frage 2
Frage
What protein condenses during apoptosis
Antworten
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Chromatin
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Actin
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Myosin
Frage 3
Frage
What form are caspases usually found in?
Antworten
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Inactive, with their DED domain tails intact
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Active, with their DED domain tails intact
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Inactive, with their DED domain tails removed
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Active, with their DED domain tails removed
Frage 4
Frage
What is required for caspase activation?
Antworten
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Addition of a DED domain tail
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Removal of the DED domain tail
Frage 5
Frage
What are the roles of the 2 main caspases?
Antworten
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3 is the initation 8 does most damage
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8 is the initiator 3 does most damage
Frage 6
Frage
Which of the following are survival/protector proteins that inhibit caspase activation?
Antworten
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BAX, BAD, PUMA
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Bci-2, Mcl1, A1
Frage 7
Frage
What is required for ligand acitvated apoptosis?
Antworten
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For the receptors to contain DED domains
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For the receptors to be bound to caspases
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For the receptors to be expressed only in certain areas of the cell membrane
Frage 8
Frage
What protein inhibits the activation of apoptic receptors?
Antworten
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Flp
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Flr
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Fld
Frage 9
Frage
Name an apoptic receptor
Antworten
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Fas
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Far
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Fam
Frage 10
Frage
How does the receptor activate caspase 8?
Antworten
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By recruiting it and cleaving off the DED domain
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By recruiting it and adding a DED domain
Frage 11
Frage
Name the two methods caspase 8 uses to destroy the cell
Antworten
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Activation of Caspase 3
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Deactivation of Caspase 3
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Damage to mitochondria, which releases Cyt. C
Frage 12
Frage
What does mitochondrial damage do to Casp 9?
Antworten
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Activates it
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Deactivates it
Frage 13
Frage
What happens when essential growth factors are withdrawn from the cell?
Antworten
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PI3K cannot activate
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PKB cannot activate
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Casp 8 cannot activate
Frage 14
Frage
How does PKB inhibit apoptosis?
Antworten
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Releases Bad from Blc-2
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Releases Blc2 from Bad
Frage 15
Frage
Identify methods which cells can use to evade apoptosis
Antworten
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Decreased Fas receptor expression
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Inc Blc2 & decrease bax/bad expression
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Loss of Casp 8
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Increased Flp expression
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Soluble fas to causes apoptosis in t-cells
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Large amounts of Fas ligand produced to kill t-cells
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