445668
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor fast 11 Jahre
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Frage 1
Frage
Which of the following can cause double strand breaks in the DNA?
Antworten
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Ionising radiation
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Meiosis
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Chemicals
-
DNA replication errors
Frage 2
Frage
What are Chromosome Fragile Sites?
Antworten
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Sites where double strand breaks are likely to occur
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Sites that can be easily split accidentally by protein machinery
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Sites that are likely to warp during heat shock
Frage 3
Frage
Chromosome fragile sites are thought to be caused by difficulties during meiosis
Antworten
- True
- False
Frage 4
Frage
What does NHEJ stand for?
Antworten
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Non-homologous end joining
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Non-homologous editing joints
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Non-heterodimeric end joints
Frage 5
Frage
What are the requirements for NHEJ?
Antworten
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Double strand breaks
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Single strand breaks
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T-T lesions
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DNA ligase 4
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DNA ligase 2
Frage 6
Frage
The repair process of NHEJ will join any 2 free ends together, regardless of homology
Antworten
- True
- False
Frage 7
Frage
An error in NHEJ can lead to translocation between which chromosomes, forming what type of chromosome fusion?
Antworten
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Philadelphia chromosome
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Inverted chromosome
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8 &12
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9 & 22
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13 & 21
Frage 8
Frage
The repair process of Homologous Recombination relies on what?
Antworten
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That the damaged sequence in the sister chromatid is intact
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That the damaged sequence in the homologous chromosome is intact
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That the damaged sequence in the other allele is intact
Frage 9
Frage
What is required for an error in Homologous Recombination?
Antworten
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A faulty alignment of the two chromosomes
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A faulty alignment of the two chromatids
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Due to inversions
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Due to translocations
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Due to repeats
Frage 10
Antworten
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NHEJ
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Homologous Recombination
Frage 11
Frage
A fault in Homologus Recombination can lead to alleles being lost
Antworten
- True
- False
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