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The Human genome is made up of approx 30,000 genes (in both mitochondrial and nuclear DNA
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How do genes code more than one protein?
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Reversed transcription
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Gene modification
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Differential splicing
Frage 3
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What is the most versitile human gene?
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The Slo gene
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The Pap gene
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The Hr4 gene
Frage 4
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The human slo gene can make up to 500 different mRNA's and works in sound regulation
Frage 5
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RNA cannot be edited after transcription
Frage 6
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What is a common method of altering RNA?
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Degrading cytosine to uracil
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Degrading thymine to uracil
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Degrading adenine to uracil
Frage 7
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Approx 20% of cytosine is methylated
Frage 8
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Cytosine methylation is restricted to where?
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C's immediately 5' of guanidine
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C's immediately 5' of adenine
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C's immediately 3' of guanidine
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C's immediately 3' of adenine
Frage 9
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Methylated cytosine can spontaneously deanimate to thymine
Frage 10
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Match the word to it's definition- where methylation is done upstream of a gene in order to pack it around the nucleosome and silence it
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De-novo methylation
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Maintentence Methylation
Frage 11
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Maintanence methylation- added to newly synthesised DNA opposite methylated groups on the parent strand
Frage 12
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Clusters in the human genome are the same as in the bacterial genome
Frage 13
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What is a multigene family?
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Where related genes of a similar function are found together
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Where related genes of different functions are found together
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Related genes with similar functions
Frage 14
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Gene families are orthologues of each other
Frage 15
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What is a pseudogene?
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An inactive gene due to faulty (partial) replication of the original
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A mutated gene that has become non-functional
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Slowly more mutations accumulate
Frage 16
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What is the difference between a pseudogene and a processed pseudogene?
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The latter has no introns or promoter
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The former contains no introns or promoter
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The latter can be used to create mRNA (though it's non functional)
Frage 17
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Processed pseudogenes are throught to be caused by the re-integration of siRNA into the genome
Frage 18
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Gene fragments are sections that look like incomplete genes
Frage 19
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Assuming the squares are all repeated units, what is the image an example of?
Frage 20
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Which of the following is not an Interpersed Repeated Intergenic DNA?
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LINES
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SINES
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DNA transposons
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MINES
Frage 21
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Interspersed Repeating Intergenic DNA are DNA sections that replicate themselves as they move around the genome.
Frage 22
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LTR's, LINE's and SINES's are transposed around the genome, how?
Frage 23
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DNA transposons also have an RNA intermediate
Frage 24
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Satellites, Minisatellites and Microsatellites are all examples of what?
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Tandemly repeated extragenic DNA
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Interspersed Replicating Integrated Elements
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Interspersed Repeating Intergenic elements
Frage 25
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Microsatellites are caused by replication slippage
Frage 26
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Tandemly Repeating Extragenic DNA is useful for what?
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Splicing
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DNA fingerprinting
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Genome mapping