Zusammenfassung der Ressource
Frage 1
Frage
Terminology:
1. [blank_start]aetiology[blank_end]: cause of disease
2. [blank_start]pathogenesis[blank_end]: the mechanism of how disease develops
3. [blank_start]morphological changes[blank_end]: structural changes in tissues and organs
4. [blank_start]clinical significance[blank_end]: functional consequences
5. [blank_start]antemortem[blank_end]: before death
6. [blank_start]postmortem[blank_end]: after death
7. [blank_start]anatomical pathology[blank_end]: postmortem and tissue biopsy
8. [blank_start]gross pathology[blank_end]: postmortem with naked eye
9. [blank_start]histopathology[blank_end]: postmortem with microscope
10. [blank_start]clinical pathology[blank_end]: analysis of body fluids and cells
Antworten
-
aetiology
-
pathogenesis
-
morphological changes
-
clinical significance
-
antemortem
-
postmortem
-
anatomical pathology
-
gross pathology
-
histopathology
-
clinical pathology
Frage 2
Frage
ATP depletion is caused by [blank_start]hypoxia[blank_end] resulting in [blank_start]decreased[blank_end] oxidative posphorylation, [blank_start]decreased[blank_end] ATP, [blank_start]increased[blank_end] anaerobic glycolysis, [blank_start]decreased[blank_end] glycogen and decreased pH. the sodium potassium pump fails and ribosomes [blank_start]detach from[blank_end] the RER.
Antworten
-
hypoxia
-
free radicals
-
decreased
-
increased
-
decreased
-
increased
-
increased
-
decreased
-
decreased
-
increased
-
detach from
-
attach to
Frage 3
Frage
the three main causes of membrane damage are:
1. [blank_start]free radicals[blank_end] that cause lipid peroxidation
2. [blank_start]direct damage[blank_end] from chemicals, viruses etc.
3. [blank_start]Hypoxia[blank_end] resulting in ATP depletion.
Antworten
-
free radicals
-
direct damage
-
Hypoxia
Frage 4
Frage
the most reactive oxygen species are [blank_start]superoxide[blank_end], [blank_start]hydrogen peroxide[blank_end] and [blank_start]hydroxyl radical[blank_end].
Antworten
-
superoxide
-
hydrogen peroxide
-
hydroxyl radical
Frage 5
Frage
which of the following are sources of free radicals?
Antworten
-
by-products of oxidative metabolism
-
phagocytic cells
-
metals
-
organophosphates
-
reperfusion following necrosis
-
reperfusion following ischaemia
-
radiation and UV light
-
drug and chemical exposure
-
nitric oxide.
Frage 6
Frage
free radicals injure cells via:
1. [blank_start]lipid peroxidation[blank_end] leading to extensive membrane damage
2. [blank_start]DNA damage[blank_end] which causes sing strand breaks
3. [blank_start]protein damage[blank_end] which causes the oxidation of amino acids
Antworten
-
lipid peroxidation
-
DNA damage
-
protein damage
Frage 7
Frage
two patterns of reversible cell injury include:
1. [blank_start]hydropic degeneration[blank_end]: acute cell swelling due to fluid influx
2. [blank_start]fatty change[blank_end]: cell swelling due to lipid accumulation
Antworten
-
hydropic degeneration
-
fatty change
Frage 8
Frage
increased cytosolic calcium is associated with reversible cell injury.
Frage 9
Frage
what type of cell injury is seen here microscopically? is it reversible?
Antworten
-
fatty change
-
hydropic degeneration
-
no it is not reversible
-
yes it is reversible
Frage 10
Frage
what type of cell injury is seen here grossly? is it reversible?
Antworten
-
fatty change
-
hydropic degeneration
-
no it is not reversible
-
yes it is reversible
Frage 11
Frage
what type of cell injury is seen here microscopically? is it reversible?
Antworten
-
fatty change
-
hydropic degeneration
-
no it is no reversible
-
yes it is reversible
Frage 12
Frage
what type of cell injury is seen here grossly? is it reversible?
Antworten
-
fatty change
-
hydropic degeneration
-
yes it is reversible
-
no it is not reversible.