Pathology of Alimentary Tract 2
(Ruminant Forestomachs/ Glandular stomach)
Description
Doctorate Pathology (Systems Pathology) Mind Map on Pathology of Alimentary Tract 2
(Ruminant Forestomachs/ Glandular stomach), created by melian.yates on 05/12/2013.
Coagulative necrosis of mucosa &
deeper structures w/ fibrin, oedema,
haemorrhage & sometimes
submucosal emphysema
Clostridium
septicum (Exotoxin)
Bacterial Gastritis &
Gastric Ulceration
Heliobacteriosis
Dogs, Cats
Helicobacter heilmannii,
Helicobacter felis
Chronic mucoid gastritis
Hypertrophic Gastritis/
Abomastitis
Chronic hypertrophic
gastritis (Dogs)
Chronic retention
of gastric fluid &
bile reflux
Marked mucosal thickening
& convolution of rugae
Histologically: Marked epithelial
hyperplasia, loss of parietal/chief
cells, dilation of mucous glands &
mixed inflammatory cell infiltrates
in lamina propria
Parasitic Gastritis (Osteragiosis)
Cattle: Ostertagia ostertagi
Sheep: Teladorsagia circumcincta
Acute Gastritis
Hyperaemia & oedema
Chronic Gastritis
Nodules (encysted larvae) in
abomasal mucosa, "Morocco
leather" appearence
Glandular hyperplasia, loss of
parietal/chief cells, chronic inflammation
associated w/ lymphocytes, plasma cells
& eosinophils & larvae
Chronic Atrophic Gastritis (Dogs)
Aetiology uncertain
Mucosal thinning & loss of gastric
glands, diffuse mixed inflammtory
infiltrate in the lamina propria
Ulceration
Pathogenesis
Hypersecretion of acid &/or
impaired mucosal barrier
=> Mucosal barrier is disrupted ->
Pepsin & acid cause Necrosis ->
Erosion/ulcers (Erosion of underlying
blood vessels -> Haemorrhage