STI (3) Diseases

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Final Exam
Sam Adeyiga
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Syphilis is caused by the siprochete -----------------? Treponema pallidum
---------------- is a specific term that is used whenever T. pallidum invades the CNS Neurosyphilis
------------ is formed during the 1st or primary stage of syphilis. 1. Chancre 2. last 3 - 6 weeks and heal without treatment
------------ are formed during the secondary stage of syphilis. 1. Palmar (skin) rash 2. mucous membrane lesions 3. Lymphadenopathy = enlarged lymph nodes 4. Condyloma latum 5. fever, pharyngitis, headache, or arthralgias
--------- are formed during tertiary stage of syphilis. 1. Neurosyphilis 2. Aortitis 3. Gummas 4. can appear 10 - 20 years after the infection was first acquired
Early latent syphilis occurs w/n --------- duration. a. One year duration from onset of infection b. the patient is still considered potentially infectious
Late latent syphilis occurs --------- duration 1. After one year 2. Patient is considered non-infectios
---------- (1), ---------- (2), -----------(3) are antibodies used for treponemal tests 1. fluorescent treponemal antibody absorbed (FTA-ABS) 2. enzyme immunoassays (EIAs) 3. T. pallidum passive particle agglutination (TP-PA).
Nontreponemal tests include --------------- and ------------ and are reported in antibody titers 1. Venereal Disease Research Lab (VDRL) 2. RPR
the preferred treatment for all stages of syphilis is ------------ ? parenteral penicillin G
Patients receiving penicillin for the treatment of syphilis should be counseled on the ------------- reaction. Jarisch-Herxheimer reaction
Jarisch-Herxheimer reaction includes ----------------- ? 1. an acute, febrile reaction 2. headache 3. myalgias *** occurs within 24 hours of treatment of syphilis
The treatment of choice for primary, secondary, or early latent syphilis is benzathine penicillin G 2.4 million units IM x 1 dose.
A patient’s nontreponemal titers should be re-checked in --------- months? 6 months
Alternatives for those penicillin-allergic include ------------? 1. doxycycline 100 mg PO bid x 14 days 2. ceftriaxone 1 g IV daily x 14 days
The treatment of choice for tertiary, late latent syphilis, or syphilis of an unknown duration is ------ ? benzathine penicillin G 2.4 million units IM q week x 3 doses.
An alternative treatment for penicillin-allergic patients and for tertiary, late latent syphilis, or syphilis of an unknown duration is ------ ? doxycycline 100 mg PO bid x 28 days
The treatment of choice for neurosyphilis is ----------? aqueous penicillin G 3 to 4 million units IV every 4 hours or as a continuous infusion for 10 to 14 days
alternative treatment for neurosyphilis is ---------- ? ceftriaxone 2 g IV daily for 10–14 days
Sexual partners of infected patients should be considered at risk and provided treatment if they had sexual contact with the patient within -------- months of the diagnosis of primary syphilis, -------- months of the diagnosis of secondary syphilis, and ------- months with early latent syphilis. a. 3 months b. 6 months c. 12 months
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