Frage | Antworten |
Cyclophosphamide | Alkylating agents N7 Guanine Nephrotoxic/Urotoxic |
Platinum Compounds | Alkylating agents N7 Guanine -platin |
Methotrexate | Antimetabolite จับ Dihydrofolate Reductase Inhibit DNA Synthesis +leucovolin (Antidote rescue) |
5-Fluorouracil | Inhibit thiamine synthase +leucovolin (Enhance) |
6-Thioguanine | Inhibit thiamine synthase +leucovolin (Enhance) |
Doxorubicin | Antibiotics จับ topoisomerase ไม่ให้คลายเกลียว Cardiotoxicity |
Vinca Alkaloids | Mitotic Inhibitors จับ B-tubulin หยุด cell ช่วง M phase Neurotoxicity |
Taxanes | Mitotic Inhibitors จับ B-tubulin หยุด cell ช่วง M phase Neurotoxicity |
Irinotecan | Topoisomerase Inhibitor Topo I |
Etoposide | Topoisomerase Inhibitor Topo II |
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