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Erstellt von Amaal Salhieh
vor mehr als 8 Jahre
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Frage | Antworten |
What is the most common cause of bronchiolitis? | RSV |
What is the second most common cause of bronchiolitis? | Parainfluenza |
Bronchiolitis is most common in what group of people? | People less than 2 yo Most common in 1st year of life |
What season does bronchiolitis peak in? | Winter |
Treatment for bronchiolitis | Supportive |
What is the most common cause of acute bronchitis? (general) | Viruses 90% of the time |
Acute bronchitis affects what age groups? | All age groups |
What season does acute bronchitis peak in? | Varies, depending on which infectious agent |
Acute bronchitis treatment | Symptomatic Abx not recommended unless bacterial |
Croup distinct clinical syndrome | barking cough |
What is the most common cause of croup? | Parainfluenza |
What is the second most common cause of croup? | RSV |
What age group is usually affected by croup? | Between 3 months and 3 years of age Peaks in year 2 |
Croup diagnosis | Primarily clinical diagnosis "Steeple sign" on xray |
Croup treatment | Keep child comfortable Take into cool night air or breathe warm mist If severe, dexamethasone (steroid) |
What is a major protein associated with paramyxoviridae? And what does it do? | F protein (fusion protein) Promotes fusion of viral and host cell membranes Can cause cell-to-cell fusion (syncytia and giant cells) |
RSV pathogenesis | DIrect invasion of respiratory epithelium (no viremia) induces syncytia formation via F ptn Spreads cell-to-cell, hiding from immune system Immunity is not long-lasting |
RSV is the most common cause of... | bronchiolitis |
RSV is the second most common cause of... | croup |
Parainfluenza virus Pathogenesis | Infects URT Cell lysis and giant cell formation Usually no viremia May spread to lower tract |
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