Major Histocompatability Complex

Beschreibung

Year 2 Karteikarten am Major Histocompatability Complex, erstellt von gina_evans0312 am 01/03/2014.
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Zusammenfassung der Ressource

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Polymorphism... Allows recognition of non self proteins/cells
MCHI- Location All nucleated cells
MCHI- Function Display of viral proteins
MCHI- No of Types 3
MCHI- Alpha1 Chain Anchors MCHI to membrane
MCHI- Beta2 Non transmembrane- binds to Alpha1 covalently
MCHI- Alpha 3 and Beta 2 Form an IgG like domain
MCHI- Size of Peptide Presented 8-10 amino acids
MCHII- Location Found solely in professional antigen presenting cells
MCHII- Alpha and Beta Chains Both attach to cell membrane (no B2 domain) with an IgG like domain
Polygenism Many genes availible
Polymorphic Many alleles availbile
MHC is both polymorphic and polygenic Accounting for its variation
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