15453328
Description
Flashcards by Sophie Byrne, updated more than 1 year ago
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Created by Sophie Byrne
about 6 years ago
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| Question | Answer |
| What are commensal flora? | Beneficial/harmless/opportunistic pathogens Can exclude pathogens Break down indigestible food |
| Give 2 examples of pathogens that are excluded by commensal flora | Candida albicans - thrush after antibiotic treatment Clostridium difficile - diarrhoea after antibiotic treatment kills of beneficial gut flora so can est itself |
| Give an example of evidence to support the idea of commensal flora breaking down indigestible food | Notobiotic mice gain weight faster than non-sterile ones - gut flora harvests additional nutrients |
| Example of probiotic species | Lactobacillus acidophilus |
| What does bifidobacterium do? | Decrease lactose intolerance Reduce serum cholesterol Anticancer activity |
| What do streptococci do and where are they found? | Opportunistic pathogen in the mouth Endocarditis if enters bloodstream of someone w/ heart problems |
| What does Haemophilus influenzae do and where is it found? | Meningitis if enters bloodstream and crosses blood-brain barrier Nose |
| What does Pseudomonas aeruginosa do and where is it found? | CF/immunocompromised: lung infections Burn wounds Skin and bowel |
| What is the Gram positive pili important for? | Bacterial adhesion Colonisation Invasion of host tissues Biofilm formation Translocation across host membranes |
| What is an example of a bacterium that uses the Gram positive pili and what does it do? | Streptococcus pneumoniae Community-acquired pneumonia (main cause) Meningitis Bacteremia Middle-ear infection |
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