22001766
Description
Flashcards by Sam Adeyiga, updated more than 1 year ago
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Created by Sam Adeyiga
over 4 years ago
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| Question | Answer |
| Syphilis is caused by the siprochete -----------------? | Treponema pallidum |
| ---------------- is a specific term that is used whenever T. pallidum invades the CNS | Neurosyphilis |
| ------------ is formed during the 1st or primary stage of syphilis. | 1. Chancre 2. last 3 - 6 weeks and heal without treatment |
| ------------ are formed during the secondary stage of syphilis. | 1. Palmar (skin) rash 2. mucous membrane lesions 3. Lymphadenopathy = enlarged lymph nodes 4. Condyloma latum 5. fever, pharyngitis, headache, or arthralgias |
| --------- are formed during tertiary stage of syphilis. | 1. Neurosyphilis 2. Aortitis 3. Gummas 4. can appear 10 - 20 years after the infection was first acquired |
| Early latent syphilis occurs w/n --------- duration. | a. One year duration from onset of infection b. the patient is still considered potentially infectious |
| Late latent syphilis occurs --------- duration | 1. After one year 2. Patient is considered non-infectios |
| ---------- (1), ---------- (2), -----------(3) are antibodies used for treponemal tests | 1. fluorescent treponemal antibody absorbed (FTA-ABS) 2. enzyme immunoassays (EIAs) 3. T. pallidum passive particle agglutination (TP-PA). |
| Nontreponemal tests include --------------- and ------------ and are reported in antibody titers | 1. Venereal Disease Research Lab (VDRL) 2. RPR |
| the preferred treatment for all stages of syphilis is ------------ ? | parenteral penicillin G |
| Patients receiving penicillin for the treatment of syphilis should be counseled on the ------------- reaction. | Jarisch-Herxheimer reaction |
| Jarisch-Herxheimer reaction includes ----------------- ? | 1. an acute, febrile reaction 2. headache 3. myalgias *** occurs within 24 hours of treatment of syphilis |
| The treatment of choice for primary, secondary, or early latent syphilis is | benzathine penicillin G 2.4 million units IM x 1 dose. |
| A patient’s nontreponemal titers should be re-checked in --------- months? | 6 months |
| Alternatives for those penicillin-allergic include ------------? | 1. doxycycline 100 mg PO bid x 14 days 2. ceftriaxone 1 g IV daily x 14 days |
| The treatment of choice for tertiary, late latent syphilis, or syphilis of an unknown duration is ------ ? | benzathine penicillin G 2.4 million units IM q week x 3 doses. |
| An alternative treatment for penicillin-allergic patients and for tertiary, late latent syphilis, or syphilis of an unknown duration is ------ ? | doxycycline 100 mg PO bid x 28 days |
| The treatment of choice for neurosyphilis is ----------? | aqueous penicillin G 3 to 4 million units IV every 4 hours or as a continuous infusion for 10 to 14 days |
| alternative treatment for neurosyphilis is ---------- ? | ceftriaxone 2 g IV daily for 10–14 days |
| Sexual partners of infected patients should be considered at risk and provided treatment if they had sexual contact with the patient within -------- months of the diagnosis of primary syphilis, -------- months of the diagnosis of secondary syphilis, and ------- months with early latent syphilis. | a. 3 months b. 6 months c. 12 months |
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