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196945
GIT Neoplasms
Description
Pathology Mind Map on GIT Neoplasms, created by Emma Jones on 08/09/2013.
No tags specified
pathology
pathology
Mind Map by
Emma Jones
, updated more than 1 year ago
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Created by
Emma Jones
about 11 years ago
115
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0
Resource summary
GIT Neoplasms
Squamous cell carcinoma: raised edge with central ulceration or white plaque
Oesophagus
Alcohol, smoking, hot beverages, nutritional deficiency, HPV
Middle 1/3 of oesophagus, grey white plaque in masses or diffuse thicknening
Insidious onset, 5yr survival 9%
Dysphagia, odynophagia, obstruction, +/- ulceration
Oropharynx
Anus: HP infection, precursor = condyloma accuminatum
Adenoma
Pleomorphic adenoma of salivary gland
Oesophagus
Colon
Dysplasia: nuclear hyperchromasia, FAP
Appendix
Adenocarcinoma
Stomach
Clinical: dyspepsia, dysphagia, altered bowel habits, nausea, anaemia
Intestinal type: bulky & glandular, Signet ring cell type: diffuse
Antrum & lesser curvature
Duodenum
Colon
Tall columnar cells, variable differentiation & gland formation
Insidious development, IDA, occult bleeding, ab cramps, BM change
Appendix
Mucocele: benign cyst
Pseudomyoma peritoneii: slow tumour, mucus production> ascites
Obstruction + enlargement mimics acute appendicitis
Lymphoma
Stomach: lymphocytic infiltrate in lamina propria
Cause chronic inflammation: EBV & H.pylori infection
Dyspepsia, epigastric pain, spreads to lymph nodes
Small intestine: Coeliac disease
Gastrointestinal stromal tumour
Stomach
Well-circumscribed mass under mucosa +/- ulceration
Epitheloid or spindle cell
Asymptomatic, bleeding, mass effect
Carcinoid tumour
Small intestine
From endocrine cells, tan polypoid lesions, intramural or submucosal +/- ulceration, island & trabeculae cell structure
More common in ileum & jejunum
Asym, ab pain, metastatic disease, obstruction
Carcinoid syndrome: ileal tumours release vasoactive substances > flushing, sweating, bronchospasm, colicky ab pain, diarrhoea
Appendix
Non-neoplastic
Colon
Inflammatory polyp: injury + regeneration cycles
Hamartoma: growth of mature tissues at site where they normally develop, FAP
Hyperplastic polyps: decreased epith turnover in >70yo
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