Question 1
Question
What is atopic eczema?
Answer
-
An inflammatory process affecting the skin
-
Loss of melanocytes from the stratum basale
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Thinning of the epidermis
Question 2
Question
Atopic eczema is not the most common form of eczema.
Question 3
Question
What percentage of the population does eczema affect?
Question 4
Question
What is the most common age of onset of atopic eczema?
Answer
-
Childhood
-
Middle age
-
Aged 60+
Question 5
Question
What conditions are often associated with atopic eczema?
Answer
-
Hayfever
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Asthma
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IBS
-
Meningitis
Question 6
Question
Histologically, which layer of skin thickens in the chronic stage of eczema?
Answer
-
Epidermis
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Dermis
-
Subcutis
Question 7
Question
In which stage of eczema is the skin likely to be weepy?
Question 8
Question
The vesicles that are present during the acute stage of atopic eczema are found....
Question 9
Question
Where does infantile atopic eczema usually first present?
Question 10
Question
What area of the body does infantile atopic eczema usually spare?
Answer
-
Face
-
Nappy area
-
Hands and feet
-
Torso
Question 11
Question
Where does eczema tend to localize to in school-age children?
Answer
-
Flexures
-
Extensor surfaces
-
Hand and feet
-
Between the digits
Question 12
Question
What is lichenification?
Answer
-
Thick, leathery skin due to extensive scratching or rubbing of the area
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Thin, papery skin due to the skin drying out
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Thickening of the skin due to the skin drying out
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Skin that has lost its pigment due to excess scratching or rubbing
Question 13
Question
Which of the following are common triggers for atopic eczema?
Answer
-
Cleaning products
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Dust mites
-
Animal fur
-
Pollens
-
Salt water
Question 14
Question
What can be used to break the itch-scratch cycle commonly seen in eczema?
Answer
-
Mittens or gloves
-
Steroids
-
Antihistamines
-
Oral antibiotics
Question 15
Question
How times a day are emollients usually prescribed for a person with eczema?
Answer
-
Once a day
-
Twice a day
-
Three times a day
-
As required
Question 16
Question
How can using soap substitutes help in the treatment of eczema?
Question 17
Question
How should steroids be used in the treatment of eczema?
Answer
-
Intermittently to control flare ups, but not on more the 7 days in a month
-
Constantly
-
As required, but not for more than a month at a time
Question 18
Question
What treatments can a dermatologist offer for eczema that a GP cannot?
Answer
-
Topical steroids
-
Systemic treatments
-
UV light therapy
-
Calcineurin inhibitors
-
Oral antibiotics
Question 19
Question
What are calcineurin inhibitors?
Answer
-
Immunomodulating drugs that block calcineurin receptors
-
Immunomodulating drugs that prevent the production of calcineurin
-
Immunomodulating drugs that decrease the effects of calcineurin by binding to it and changing its shape
Question 20
Question
What does calcineurin do?
Answer
-
Activates inflammation within the skin
-
Causes immune cells within the skin to proliferate
-
Aggravates the skin causing inflammation
Question 21
Question
Steroids can cause stretch marks or striae on the skin.
Question 22
Question
What is the most common bacterial infection that accompanies eczema?
Answer
-
Staphylococcal infection
-
E. Coli infection
-
Streptococcal infection
Question 23
Question
What is the most common viral co-infection that accompanies eczema?
Answer
-
Herpes infection
-
Rhotavirus infection
-
Coronovirus infection
Question 24
Question
When is hyper- or hypo- pigmentation most likely to occur in eczema?
Question 25
Question
Eczema does not cause scarring. True or false?
Question 26
Question
Where does psoriasis most often occur on the body?
Answer
-
Flexor surfaces
-
Extensor surfaces
-
Torso
-
Extremities
Question 27
Question
Which of these descriptions most accurately describes psoriasis?
Answer
-
Well-defined, inflamed plaques which appear white and scaly
-
Poor-defined, inflamed plaques which appear white and scaly
-
Well-defined, inflamed plaques which appear golden and crusty
-
Poorly-defined, inflamed plaques which appear golden and crusty
Question 28
Question
What percentage of the population is affected by psoriasis?
Answer
-
0.1-0.5%
-
1-2%
-
5-7%
-
10-15%
Question 29
Question
What is the peak age of onset for psoriasis?
Answer
-
15 years old
-
28 years old
-
40 years old
-
67 years old
Question 30
Question
Psoriasis only affects women. True or false?
Question 31
Question
Psoriasis usually affects extensor surfaces, but where else can it commonly affect?
Question 32
Question
The distribution of psoriasis is usually symmetrical. True or false?
Question 33
Question
Histologically, what occurs in psoriasis?
Answer
-
Disordered maturation of keratinocytes
-
Increased epidermal transit time of keratinocytes
-
Thickening of the epidermis
-
Hyperplasia of keratinocytes in the stratum corneum
-
Benign proliferation of Langerhan cells within the epidermis
Question 34
Question
How does coal tar help to treat psoriasis?
Answer
-
Slows the growth of keratinocytes
-
Restores the skins appearance
-
Reduces the irritation of the skin
-
Thins the epidermis
-
Slows hair growth
Question 35
Question
Why is coal tar not well tolerated?
Answer
-
It can make the skin red and itchy
-
It can stain clothes, bedding and light-coloured hair
-
It causes hair loss
-
Not very much improvement is seen after short-term use
Question 36
Question
How is salicylic acid useful in treating psoriasis?
Question 37
Question
What is the mechanism of action of vitamin D analogues used in the treatment of psoriasis?
Answer
-
Reduces proliferation of keratinocytes and stimulates epidermal cell differentiation
-
Reduces proliferation of melanocytes and stimulated epidermal cell differentiation
-
Increases proliferation of keratinocytes and stimulates epidermal cell differentiation
-
Reduces proliferation of keratinocytes and reduces epidermal cell differentiation
Question 38
Question
What treatments can dermatologists offer for psoriasis that GPs cannot?
Answer
-
Topical steroids
-
UV phototherapy
-
Systemic medications
-
Monoclonal antibodies
-
Emollients
-
Coal tar
Question 39
Question
Which wavelength of UV light is used in UV phototherapy?
Question 40
Question
Why are oral retinoids given before a course of UV phototherapy?
Answer
-
To enhance the effects of the UV phototherapy
-
To sedate the patient
-
To ensure the patient does not experience and nausea or vomiting
-
To reduce the risk of DNA damage to skin cells
Question 41
Question
What is the course of treatment for UV phototherapy?
Answer
-
2-3 times per week for 3-4 months
-
As required
-
6 times per week for a month
-
Once per week for one year
Question 42
Question
What is the cause of acne vulgaris?
Answer
-
Over-activity of pilo-sebaceous glands
-
Over-activity of apocrine sweat glands
-
Over-activity of eccrine sweat glands
-
Under-activity of pilo-sebaceous glands
Question 43
Question
What causes the over stimulation of the sebaceous glands?
Question 44
Question
How does the over stimulation of the sebaceous glands then lead to acne?
Answer
-
The hair follicles become "plugged" with secretions
-
Inflammation occurs within the hair follicles
-
Hair growth is too fast due to increased sebum leading to the follicle becoming blocked
Question 45
Question
Where on the body is acne most common?
Answer
-
Face
-
Upper chest and back
-
Hands
-
Scalp
Question 46
Question
Why is acne most common on the face, upper chest and upper back?
Answer
-
Because the highest population of sebaceous glands is found here
-
Because these areas are often exposed
-
Because these areas are most often touched with dirty hands
Question 47
Question
How many grades of severity are there for acne vulgaris?
Question 48
Question
What do topical retinoids do?
Question 49
Question
How should systemic retinoids not be given to?
Question 50
Question
How is the oral contraceptive pill useful in treating acne?
Answer
-
It controls the hormones to prevent over stimulation
-
It makes sebum less viscous preventing "plugging" of the hair follicles
-
It makes hair follicles larger so that they become "plugged" less easily
-
It is used in women and girls to give a placebo effect
Question 51
Question
Both oral and topical antibiotics can be used to treat acne vulgaris. True or false?
Question 52
Question
What type of infection is impetigo?
Question 53
Question
Which bacteria are most commonly responsible for impetigo?
Question 54
Question
What feature is very characteristic of impetigo?
Question 55
Question
What two treatments are most commonly used to treat impetigo?
Answer
-
Fucidin cream
-
Oral flucloxadin
-
Topical penicillin
-
Emollients
-
Methotrexate
-
Topical dexamethasone
Question 56
Question
What virus usually causes viral warts?
Question 57
Question
How are viral warts most commonly transmitted?
Question 58
Question
Viral warts are often self-resolving. True or false?
Question 59
Question
Which of the following is not a treatment for viral warts?
Question 60
Question
Tinea and roundworm are different skin conditions. True or false?
Question 61
Question
What is tinea caused by?
Answer
-
A bacteria
-
A virus
-
A fungus
Question 62
Question
What is the usually given as treatment for tinea?
Answer
-
Topical anti-fungals
-
Topical antibiotics
-
Emollients
-
Topical corticosteroids
Question 63
Question
Systemic treatment is never used for tinea infection. True or false?
Question 64
Question
What causes actinic keratosis?
Answer
-
Sun exposure
-
Benign proliferation of melanocytes
-
Hormonal over-stimulation
-
Wear and tear of the skin over time
Question 65
Question
In what age group is actinic keratosis most common?
Answer
-
Over sixties
-
Forties to fifties
-
Teenagers
-
Infants
Question 66
Question
Why must actinic keratosis be closely observed?
Answer
-
Because it can develop into skin cancer
-
Because as it increases in size it can become very painful
-
Because if a person has more than three lesions they may have liver cirrhosis
Question 67
Question
What skin cancer is actinic keratosis most likely to develop into?
Answer
-
Melanoma
-
Squamous cell carcinoma
-
Basal cell carcinoma
Question 68
Question
What treatments are there for actinic keratosis?
Answer
-
Cryptherapy
-
Emollients
-
Topical corticosteroids
-
Systemic retinoids
-
Oral antibiotics
Question 69
Question
Which type of skin cancer is considered to be the least serious?
Answer
-
Basal cell carcinoma
-
Squamous cell carcinoma
-
Melanoma
Question 70
Question
Where on the body does basal cell carcinoma most commonly present?
Answer
-
Head and neck
-
Hands and arms
-
Torso
-
Any sun exposed area
Question 71
Question
What is the appearance of a basal cell carcinoma lesion?
Answer
-
Shiny, translucent nodule
-
Dark, asymmetrical lesion
-
Inflamed, crater-shaped lesion
Question 72
Question
Why is basal cell carcinoma not referred under the two week wait rule?
Answer
-
Because it very rarely metastasizes
-
Because nothing can be done to remove this cancer
-
Because too many people get this type of cancer for the NHS to deal with
Question 73
Question
Squamous cell carcinoma only arises from actinic keratosis. True or false?
Question 74
Question
What is squamous cell carcinoma caused by?
Question 75
Question
What features of a skin lesion would make it suspicious?