The substrates for the synthesis of cholesterol are AcetylCoA, ATP and NADPH
30 reactions occur in cholesterol synthesis
The regulation of the synthesis takes place in the first step
Synthesis of cholesterol happens in a fasting state
Synthesis of cholesterol will take place in liver in the cytosol
Question 4
Question
Which enzyme can be blocked using statins leading to a regulation in the production of mevalonic acid?
Answer
Thiolase
HMG-CoA synthase
HMG-CoA reductase
Squalene synthase
Prenyl transferase
Question 5
Question
Which molecule or molecules is/are inhibitors of the synthesis of cholesterol?
Answer
Cholesterol
Glucagon
NADPH
ATP
Glucagon and cholesterol
Question 6
Question
What is found in the surface of a lipoprotein?
Answer
Cholesterol esters and triglycerides
Proteins, phospholipids (the head) and the hydroxyl group of cholesterol
The hydroxyl group of cholesterol
Proteins and triglycerides
Cholesterol esters, triglycerides and proteins
Question 7
Question
Which is the biggest lipoprotein?
Answer
Chylomicrons
VLDL's
IDL's
LDL's
HDL's
Question 8
Question
Which lipoprotein transport phospholipids?
Answer
Chylomicrons
VLDL's
IDL's
LDL's
HDL's
Question 9
Question
If the levels of HDL cholesterol are higher that the levels of LDL this means that you have more bad cholesterol and you are deporting more cholesterol from liver to the tissues than the cholesterol that is transported from the tissues to the liver
Answer
True
False
Question 10
Question
Which of these statements is true?
Answer
Any of these
Lipoprotein lipase is responsible for the transformation of Fatty Acids and glycerol into TG
Lipoprotein lipase is responsible for the transformation of TG and glycerol into Fatty Acids
Lipoprotein lipase is responsible for the transformation of Fatty Acids into TG and glycerol
Lipoprotein lipase is responsible for the transformation of Glycerol into Fatty Acids and TG
Question 11
Question
What could happen if you find high levels of chylomicrons in a clinical analysis?
Answer
The patient is in a fasting state
The patient is in a fed state
The patient could have a disorder due to the endogenous pathway
The patient could have a disorder due to the reverse transport of cholesterol