PHSI3011 06-1 Neural Control of Breathing

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PHSI3011 06-1 Neural Control of Breathing
Michael Jardine
Test por Michael Jardine, actualizado hace más de 1 año
Michael Jardine
Creado por Michael Jardine hace alrededor de 7 años
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Resumen del Recurso

Pregunta 1

Pregunta
What’s the major factor that drives breathing?
Respuesta
  • Blood CO2 level
  • Blood H+ level
  • Blood O2 level
  • Pacemaker-like cells
  • Blood pH
  • Vagal stimulation
  • Vagal inhibition

Pregunta 2

Pregunta
Label the blanks:
Respuesta
  • Phrenic
  • Vagal
  • Inspiration
  • Expiration

Pregunta 3

Pregunta
The rate and depth of respiration are regulated by: 1 – Inputs to the respiratory centre signalling the Pco2, pH, AND Po2 of the [blank_start]__________[blank_end] blood; 2 – Afferent (sensory) inputs from receptors in the [blank_start]__________[blank_end]; 3 – Inputs arising from higher centres of the brain, such as the motor cortex.
Respuesta
  • Arterial
  • Venous
  • Lungs
  • Kidney

Pregunta 4

Pregunta
What's this bit? (responsible for responding to CO2)
Respuesta
  • RetroTrapezoid Nucleus (RTN)
  • RetroTrapezoid Fibrillary Medulla (RTFM)

Pregunta 5

Pregunta
DRG = ??
Respuesta
  • Dorsal Root Ganglion
  • Dorsal Respiratory Group
  • “Dickheads are Racists” Group

Pregunta 6

Pregunta
VRG = ??
Respuesta
  • Ventral Root Ganglion
  • Ventral Respiratory Group
  • “Vickheads are Racists” Group

Pregunta 7

Pregunta
DRG neurons consist [blank_start]__________[blank_end], whereas VRG neurons consist of [blank_start]__________[blank_end].
Respuesta
  • Mainly of inspiratory neurons
  • Mainly of expiratory neurons
  • Both inspiratory and expiratory neurons

Pregunta 8

Pregunta
Neurons in the pontine “[blank_start]__________[blank_end] centre” [blank_start]__________[blank_end] inspiratory neurons, thus LIMITING inspiration.
Respuesta
  • Pneumotaxic
  • Apneustic
  • Inhibit
  • Excite

Pregunta 9

Pregunta
Neurons in the pontine “[blank_start]__________[blank_end] centre” [blank_start]__________[blank_end] inspiratory neurons, thus PROMOTING inspiration.
Respuesta
  • Pneumotaxic
  • Apneustic
  • Inhibit
  • Excite

Pregunta 10

Pregunta
[blank_start]__________[blank_end] is usually a passive process.
Respuesta
  • Inspiration
  • Expiration

Pregunta 11

Pregunta
Mutations for the Phox2b transcription factor result in Congenital Central Hypoventilation Syndrome (CCHS) which causes an almost complete loss of respiratory response to what?
Respuesta
  • Increased CO2
  • Exercise
  • Arousal

Pregunta 12

Pregunta
True or false: Phox2b is expressed in the cerebellum.
Respuesta
  • True
  • False

Pregunta 13

Pregunta
True or false: Phox2b is not expressed in neurons above the pons.
Respuesta
  • True
  • False

Pregunta 14

Pregunta
RTN = ??
Respuesta
  • RetroTrapezoid Nucleus
  • Rostral Trapezoid Nucleus
  • RetroTrapezoid Nerves
  • Rostral Trapezoid Nerves

Pregunta 15

Pregunta
Which of the following is known as the “Hering-Breuer reflex”?
Respuesta
  • Pulmonary stretch receptors are excited as the lungs inflate > nerve impulses to the respiratory centre in brainstem via nerve fibres in the VAGUS nerve > inhibition of inspiration
  • Pulmonary stretch receptors are excited as the lungs inflate > nerve impulses to the respiratory centre in brainstem via nerve fibres in the PHRENIC nerve > inhibition of inspiration
  • Increase of CO2 is sensed by the central chemoreceptors > excitation of inspiration stimulus by the VAGUS nerve
  • Increase of CO2 is sensed by the central chemoreceptors > excitation of inspiration stimulus by the PHRENIC nerve

Pregunta 16

Pregunta
Central vs Peripheral chemoreceptors. The Central chemoreceptors reside in the [blank_start]__________[blank_end], whereas the Peripheral chemoreceptors reside in the [blank_start]__________[blank_end].
Respuesta
  • RTN
  • Carotid body

Pregunta 17

Pregunta
Central vs Peripheral chemoreceptors. The Central chemoreceptors detect [blank_start]__________[blank_end], whereas the Peripheral chemoreceptors detect [blank_start]__________[blank_end].
Respuesta
  • HIGH CO2
  • LOW C02
  • HIGH O2
  • LOW O2

Pregunta 18

Pregunta
Upon submersion (or irritation stimulus), the nasopharyngeal reflex (aka “diving reflex”) triggers a(n) [blank_start]__________[blank_end] of Sympathetic vasomotor activity, which results in [blank_start]__________[blank_end] TPR. It also triggers a(n) [blank_start]__________[blank_end] in Cardiac vagal activity, which results in a decreased HR and decreased CO. The net effect of this is [blank_start]__________[blank_end] Oxygen conservation.
Respuesta
  • Increase
  • Decrease
  • Increased
  • Decreased
  • Increase
  • Decrease
  • Increased
  • Decreased

Pregunta 19

Pregunta
Diving results in:
Respuesta
  • Bradycardia
  • Tachycardia
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