Pregunta 1
Pregunta
If all the nerves passing through the annulus of Zinn were transected, what nerve would
continue to function?
Pregunta 2
Pregunta
Which extraocular muscle originates from the annulus of Zinn?
Pregunta 3
Pregunta
What is the ratio of optic nerve axons that cross at the optic chiasm to those that do not cross at the optic chiasm?
Pregunta 4
Pregunta
A patient presents with left-sided ophthalmoplegia and forehead numbness. The lesion is
most likely to be located at the:
Respuesta
-
Brainstem
-
Cavernous sinus
-
Superior Orbit
-
Intraconal space
Pregunta 5
Pregunta
The first cells to develop in the embryonic retina are the:
Respuesta
-
Ganglion cells
-
Photoreceptors
-
Amacrine Cells
-
Bipolar cells
Pregunta 6
Pregunta
Which disorder is associated with a non-mitochondrial gene?
Respuesta
-
Leber hereditary optic neuropathy
-
Chronic Progressive External Ophthalmoplegia
-
Neuropathy, ataxia, and retinitis pigmentosa
-
Retinoblastoma
Pregunta 7
Pregunta
What characteristic of retinoblastoma may facilitate its diagnosis as a familial condition?
Respuesta
-
It may be associated with chromosome 11 short-arm deletion syndrome and Wilms
tumor.
-
It affects approximately 1 per 100,000 live births in the United States.
-
Approximately 90% of patients with hereditary retinoblastoma have a family history of
the disease.
-
The hereditary pattern in familial retinoblastoma is autosomal dominant, but the defect is mitochondrial at a cellular level.
Pregunta 8
Pregunta
Mutations in the rhodopsin gene are associated with what inherited ocular disease?
Pregunta 9
Pregunta
Mitochondrial inheritance is transmitted by what route?
Respuesta
-
Paternal mitochondria
-
Maternal mitochondria
-
Acquired mitochondria
-
De novo mitochondria
Pregunta 10
Pregunta
Mutations of PAX6 are associated with what disorder?
Pregunta 11
Pregunta
An unaffected woman has a brother, maternal uncle, and son affected with retinitis pigmentosa. What is the most likely mode of inheritance?
Respuesta
-
Autosomal dominant
-
X-linked recessive
-
Autosomal recessive
-
sporadric
Pregunta 12
Pregunta
What is the basis for complex genetic diseases?
Respuesta
-
A single recessive gene
-
X-linked genes
-
A single spontaneous genetic mutation
-
The resultant effect of many genes, in combination with health habits and environmental factors
Pregunta 13
Pregunta
What structure, if inflamed, would be considered a sign of uveitis?
Pregunta 14
Pregunta
What pair accurately matches a cell-type origin with the correct tear-layer product?
Respuesta
-
Goblet cells - Lipid Layer
-
Meibomian Glands - Mucin Layer
-
Glands of Krause - Aqueous layer
-
Glands of Wolfring - Mucin layer
Pregunta 15
Pregunta
What option most accurately describes the immunoglobulin(s) that can be found in the tear film?
Respuesta
-
IgA only
-
IgA and IgG only
-
IgG and IgM only
-
IgA, IgG, IgM, and IgD
Pregunta 16
Pregunta
What intraocular structure is a true basement membrane (basal lamina)?
Pregunta 17
Pregunta
What is the principal structural protein in the Descemet membrane
Respuesta
-
Type I collagen
-
Type II collagen
-
Type III collagen
-
Type IV collagen
Pregunta 18
Pregunta
What mechanism holds the flap created during laser in situ keratomileusis (LASIK) in place after surgery?
Respuesta
-
endothelial - Descemet membrane interaction
-
endothelial pump
-
Bowman layer - stromal adhesions
-
stromal collagen adhesions
Pregunta 19
Pregunta
What property of the retina renders it susceptible to oxidative stress?
Respuesta
-
high content of polyunsaturated fatty acids in the photoreceptor outer segments
-
high concentration of carotenoids compared with other intraocular structure
-
presence of Vitamin E
-
absence of retinal vessels in the foveal avascular zone
Pregunta 20
Pregunta
What pigment within the retinal pigment epithelium is responsible for the signal generated in fundus autofluorescence imaging?
Respuesta
-
melanin
-
lipofuscin
-
rhodopsin
-
lutein
Pregunta 21
Pregunta
The retinal pigment epithelium is the first site of melanogenesis in the body. Ocular melanin has been shown to participate in what process?
Pregunta 22
Pregunta
Age-related loss of type IX collagen has been implicated in what process related to the vitreous?
Pregunta 23
Pregunta
What vitamin is most critical for the photoreceptor response to light
Pregunta 24
Pregunta
In prescribing for elderly patients, what pharmacologic adjustments should be considered?
Respuesta
-
Hepatic perfusion and enzymatic activity increase with age.
-
Renal function decreases with age.
-
Elderly patients have more albumin relative to weight.
-
Elderly patients have more body water relative to weight
Pregunta 25
Pregunta
What technique or strategy improves the ocular absorption of eyedrops?
Respuesta
-
Rapid instillation of eyedrops one after the other without interruption
-
Application of digital pressure at the lateral canthus to prevent the eyedrop from escaping
-
Keeping the eye open and rolling the eye around after instillation of each drop
-
Increasing the viscosity of the delivery vehicle
Pregunta 26
Pregunta
Atropine, 1%, has how many milligrams of drug per drop, assuming 20 drops per milliliter?
Respuesta
-
1 mg
-
0.5 mg
-
0.1 mg
-
0.05 mg
Pregunta 27
Pregunta
How much epinephrine is present in 1 mL of the 1:10,000 epinephrine solution?
Respuesta
-
1 mg of epinephrine
-
same amount of epinephrine as in 1 mL of 0.01% epinephrine
-
same amount of epinephrine as in 1 mL of 1:1000 epinephrine
-
Same amount of epinephrine as in 1 mL of 0.1% epinephrine
Pregunta 28
Pregunta
Direct-acting muscarinic agents (miotics) have what clinical effect?
Respuesta
-
hyperopic shift in refraction
-
increased range of accomodation
-
central anterior chamber deepening
-
increased night vision
Pregunta 29
Pregunta
What management strategy has been shown to reduce postsurgical endophthalmitis?
Respuesta
-
preoperative preparation of the eye with topical povidone-iodine
-
intracameral vancomycin
-
intracameral aminoglycosides
-
subconjunctival fluoroquinolones
Pregunta 30
Pregunta
What property of latanoprost may limit its usefulness?
Respuesta
-
It is a prodrug of prostaglandin E20 .
-
It reduces intraocular pressure by increasing trabecular meshwork outflow
-
It can cause darkening ofthe iris and periocular skin and hypertrichosis ofthe eyelashes
-
It increases the number of melanocytes
Pregunta 31
Pregunta
What systemic side effect may result from treatment with oral carbonic anhydrase inhibitors?
Respuesta
-
Insomnia
-
Weight gain
-
Hyperkalemia
-
Aplastic anemia
Pregunta 32
Pregunta
What is a clinically important property of brimonidine?
Respuesta
-
Brimonidine is a selective a 1-adrenergic agonist.
-
Brimonidine is more lipophilic than apraclonidine.
-
Brimonidine has been associated with tachycardia and hyperventilation when used in
infants.
-
Rates of tachyphylaxis and allergic reaction are higher in brimonidine than in apraclonidine