Pregunta 1
Pregunta
Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:
Respuesta
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80 y.o. female patient 2 days after 40% body surface area burn
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18 y. o. male one week after spinal cord transection injury
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12 y.o. with Duchene’s muscular dystrophy
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22 y. o. with evolving respiratory failure secondary to Guillian-Barre’
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27 y. o. female with myasthenia gravis
Pregunta 2
Pregunta
A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:
Respuesta
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Quinidine
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Phenytoin
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Cyclophosphamide
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Aminoglycosides
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Magnesium
Pregunta 3
Pregunta
The MOST important parameter that determines the speed of onset for NMB drugs is:
Respuesta
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Potency
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Lipophilicity
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Ionization
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Plasma clearance
-
E. Receptor affinity
Pregunta 4
Pregunta
A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:
Respuesta
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Significant histamine release after a bolus injection
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Vagolysis producing tachycardia
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Hofmann elimination
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Deacetylation in the liver
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Production of laudanosine as the primary metabolite
Pregunta 5
Pregunta
Clinical data support that when the TOFR exceeds [blank_start]__[blank_end],
anesthesia providers have trouble assessing the presence
of fade
Pregunta 6
Pregunta
TOF count of 3 would equate to a twitch suppression of [blank_start]__[blank_end]%
Pregunta 7
Pregunta
Once the TOF ratio exceeds [blank_start]0.60[blank_end], fade to DBS generally cannot be detected subjectively
Pregunta 8
Pregunta
What is true about Tetanic stimulation (TET)?
Respuesta
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During partial depolarizing block, fade is not observed in response to tetanic stimulation
-
Tetanic stimulation is not painful
-
Muscular fatigue usually develop at a stimulation frequency of 50 Hz
-
Fade is thought to be an effect of a depolarizing agent on the presynaptic nerve membrane
Pregunta 9
Pregunta
Which statement about posttetanic count is NOT correct?
Respuesta
-
The number of posttetanic count twitches is inversely related to time until the first regular TOF twitch returns
-
Posttetanic count used when TOF or DBS is absent to estimate recovery time
-
Posttetanic count uses tetany followed by TOF at frequency of 1 Hz
-
The main use of posttetanic count is when profound neuromuscular block is not required
Pregunta 10
Pregunta
Correct statements about objective monitoring techniques include:
Respuesta
-
Mechanomyography (MMG) measures isotonic contraction of peripheral muscles in response to nerve stimulation
-
Acceleromyography (AMG) calculates the force of contraction of a muscle using a miniature piezoelectric transducer
-
Electromyography (EMG) measures the electrical activity (compound muscle action potential) of a stimulated muscle
-
Kinemyography (KMG) detects the acceleration of the thumb contraction in response to electrical stimulation of a nerve
Pregunta 11
Pregunta
All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:
Respuesta
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D-tubocurarine
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Atracurium
-
Mivacurium
-
Pancuronium
-
Cisatracurium
Pregunta 12
Pregunta
Train-of-four (TOF) has all of the following characteristics, EXCEPT:
Respuesta
-
TOF consists of four ST stimuli at a frequency of 4 Hz
-
TOF does not require a “baseline” or “control” muscle response
-
TOF “fade” is defined as a weaker fourth twitch than the first twitch
-
TOF is delivered every 15-20 sec to prevent potentiation of subsequent responses
-
TOF ratios >0.40 cannot be reliably detected subjectively (visually or tactilely)
Pregunta 13
Pregunta
Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:
Respuesta
-
The two mini-tetanic bursts are separated by 0.5 sec
-
DBS is delivered no more frequently than every 20 sec to prevent subsequent response potentiation
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In DBS, similar to TOF pattern, no control (“baseline”) muscle response is needed
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DBS ratios >0.60 cannot be reliably detected by subjective (tactile, visual) means
-
In awakening patients, DBS is more painful than TOF, but less so than tetanic stimulation
Pregunta 14
Pregunta
Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:
Respuesta
-
Myalgia
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Tachycardia
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Anaphylaxis
-
Hyperkalemia
Pregunta 15
Pregunta
Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.
Pregunta 16
Pregunta
When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:
Respuesta
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Verapamil
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Dexamethasone
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Ranitidine
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Odansetron