Pregunta 1
Pregunta
Brain tumours can be described as supratentorial and infratentorial based on their position in relation to the [blank_start]tentorium cerebelli[blank_end]
Pregunta 2
Pregunta
Which benign brain tumour of the pituitary gland is known to cause bitemporal hemianopia in children due to compression of the optic chiasm?
[blank_start]Craniopharyngioma[blank_end]
Pregunta 3
Pregunta
One of the main red flags for a brain tumour is a headache which is worse [blank_start]in the morning[blank_end]
Respuesta
-
in the morning
-
at night
-
during exercise
Pregunta 4
Pregunta
Whilst an intrinsic brain tumour affects the brain itself, an extrinsic brain tumour affects which of the following 2 structures?
Respuesta
-
Bone
-
Meninges
-
Spinal cord
-
Nasal cavity
Pregunta 5
Pregunta
Cushing's triad is a series of signs/symptoms that are indicative of possible impending fatal herniation of the brain.
What are the constituents of this triad?
Pregunta 6
Pregunta
A patient showing signs of Cushing's triad should be immediately rushed to surgery for decompression. Which diuretic drug should be given in the meantime to ensure they don't pass away before reaching theatre?
[blank_start]Mannitol[blank_end]
Pregunta 7
Pregunta
A patient with a known brain tumour is unable to perform three separate motor functions in a row (such as rock, paper, scissors). It is likely their tumour is affecting which part of the brain?
Respuesta
-
Frontal lobe
-
Parietal lobe
-
Temporal lobe
-
Occipital lobe
-
Insular lobe
Pregunta 8
Pregunta
Which are the main two imaging modalities for brain tumour diagnosis?
Respuesta
-
CT
-
MRI
-
X-ray
-
Ultrasound
-
PET scan
-
Angiogram
Pregunta 9
Pregunta
What is the most common type of brain tumour?
Respuesta
-
Metastases from cancer process elsewhere in the body
-
Meningiomas
-
Neuroepithelial tissue cancers
-
Nerve sheath cell cancers
Pregunta 10
Pregunta
Neuroepithelial tissue brain tumours can arise from any of the following cell types, however which is the most common?
Respuesta
-
Astrocytes
-
Oligodendrocytes
-
Ependymal cells
-
Neuronal cells
-
Pineal cells
Pregunta 11
Pregunta
There are [blank_start]4[blank_end] WHO gradings of astrocytic tumours
Pregunta 12
Pregunta
The only truly benign astrocytoma is...
Respuesta
-
Grade I astrocytoma
-
Grade II astrocytoma
-
Grade III astrocytoma
-
Grade IV astrocytoma
Pregunta 13
Pregunta
Of all astrocytomas, which most commonly occur in children?
Respuesta
-
Grade I astrocytoma
-
Grade II astrocytoma
-
Grade III astrocytoma
-
Grade IV astrocytoma
Pregunta 14
Pregunta
What is the most typical mode of treatment for a grade I astrocytoma?
Respuesta
-
Surgery
-
Chemotherapy
-
Radiotherapy
Pregunta 15
Pregunta
Low grade astrocytomas are also known as
Respuesta
-
Grade I astrocytoma
-
Grade II astrocytoma
-
Grade III astrocytoma
-
Grade IV astrocytoma
Pregunta 16
Pregunta
What tends to be the main presentation of low grade astrocytomas?
Respuesta
-
Headaches
-
Seizures
-
Diplopia
-
Nausea+Vomiting
Pregunta 17
Pregunta
Low grade (Grade II) astrocytomas tend to affects people [blank_start]over[blank_end] 50
Pregunta 18
Pregunta
Low grade astrocytomas don't tend to differentiate into higher grade tumours (Grade III/IV) and therefore surgery is not recommended. Instead, serial imaging and potential chemo/radiotherapy is the mainstay of treatment.
Pregunta 19
Pregunta
Of the malignant astrocytomas, which is by far the most common?
Respuesta
-
Anaplastic Astrocytoma
-
Glioblastoma Multiforme
Pregunta 20
Pregunta
Grade III Astrocytoma = [blank_start]Anaplastic Astrocytoma[blank_end]
Grade IV Astrocytoma = [blank_start]Glioblastoma Multiforme[blank_end]
Respuesta
-
Glioblastoma Multiforme
-
Anaplastic Astrocytoma
Pregunta 21
Pregunta
Which treatment has been proven to be most effective in treating brain tumours?
Pregunta 22
Pregunta
Meningiomas are the most common [blank_start]benign[blank_end] intracranial tumour. They arise from [blank_start]arachnoid[blank_end] cap cells in the meninges.
Respuesta
-
arachnoid
-
dura
-
pia
-
benign
-
malignant
Pregunta 23
Pregunta
There are four aggressive meningiomas. What are they?
Pregunta 24
Pregunta
How are meningiomas typically managed?
Respuesta
-
Surgery
-
Chemotherapy
-
Radiotherapy
Pregunta 25
Pregunta
A nerve sheath tumour originating in the myelin producing cells of the PNS is called a [blank_start]Schwannoma[blank_end]
Pregunta 26
Pregunta
A [blank_start]Vestibular Schwannoma[blank_end] is a tumour of the myelin forming cells of the 8th cranial nerve (vestibulocochlear nerve).
Pregunta 27
Pregunta
Vestibular Schwannomas tend to occur in patients with the condition [blank_start]Neurofibromatosis Type II[blank_end]
Pregunta 28
Pregunta
The most common CNS germ cell tumour is...
Respuesta
-
Germinoma
-
Teratoma
-
Yolk sac Tumour
-
Choriocarcinoma
Pregunta 29
Pregunta
There are 3 main tumour markers for germ cell tumours. Therefore, in a child with a midline brain tumour which 3 markers should be tested for?
Respuesta
-
Alpha Fetoprotein (AFP)
-
Human Choriogonadotrophin (bHCG)
-
Placental Alkaline Phosphatase (pALP)
-
Carcinoembryonic Antigen (CA)
-
CA-125 Protein
Pregunta 30
Pregunta
Which type of drug can be used to shrink a Prolactinoma?
Pregunta 31
Pregunta
Name the dopamine receptor agonist used most frequently to shrink Prolactinomas
[blank_start]Cabergoline[blank_end]
Pregunta 32
Pregunta
The main therapy of choice for Acromegaly is the use of [blank_start]Somatostatin[blank_end] Analogues
Pregunta 33
Pregunta
Which of the following is a somatostatin analogue that can be used to treat acromegaly?
Respuesta
-
Octreotide
-
Lansoprazole
-
Pramipexole
-
Metyrapone
Pregunta 34
Pregunta
Tumour markers in germ cell tumours:
AFP present = [blank_start]Yolk Sac Tumour[blank_end]
Beta-hCG present = [blank_start]Choriocarcinoma[blank_end]
PLAP present = [blank_start]Germinoma[blank_end]
Respuesta
-
Germinoma
-
Choriocarcinoma
-
Yolk Sac Tumour