Pregunta 1
Pregunta
What is the most common form of Motor Neuron Disease?
Respuesta
-
Amyotrophic Lateral Sclerosis (ALS)
-
Hereditary Spastic Paraplegia (HSP)
-
Primary Lateral Sclerosis (PLS)
Pregunta 2
Pregunta
Which type of motor neuron disease exhibits both upper and lower motor neuron degeneration?
Respuesta
-
Hereditary Spastic Paraplegia (HSP)
-
Primary Lateral Sclerosis (PLS)
-
Amyotrophic Lateral Sclerosis (ALS)
Pregunta 3
Pregunta
Which type fo Motor Neuron Disease is also referred to as Lou Gehrig's Disease?
Respuesta
-
Hereditary Spastic Paraplegia (HSP)
-
Primary Lateral Sclerosis (PLS)
-
Amyotrophic Lateral Sclerosis (ALS)
Pregunta 4
Pregunta
Amyotrophic Lateral Sclerosis typically presents at what age?
Respuesta
-
Around 40
-
Around 20
-
Around 60
-
Teenage years
Pregunta 5
Pregunta
The average survival for patients diagnosed with ALS is [blank_start]2-4[blank_end] years, with most eventually dying of [blank_start]respiratory[blank_end] failure
Respuesta
-
respiratory
-
heart
-
cerebral
-
2-4
-
10-20
-
15-20
Pregunta 6
Pregunta
The most common symptoms of onset in ALS are spinal onset and bulbar onset. Match the type of onset to its symptoms:
[blank_start]Spinal onset (65%)[blank_end] = Presents with progressive weakness in the arms and the legs
[blank_start]Bulbar onset (25%)[blank_end] = Presents with progressive weakness in the muscles of speech, chewing & swallowing.
Respuesta
-
Bulbar onset (25%)
-
Spinal onset (65%)
Pregunta 7
Pregunta
Which of the following describe Babinski sign
Respuesta
-
Firm stroking of the sole of the foot causes plantarflexion of the foot
-
Firm stroking of the sole of the foot causes dorsiflexion of the foot
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Firm stroking of the sole of the foot causes eversion of the foot
-
Firm stroking of the sole of the foot causes inversion of the foot
Pregunta 8
Pregunta
A clonic jaw reflex would suggest which type of ALS onset?
Respuesta
-
Bulbar onset
-
Spinal onset
-
Respiratory onset
Pregunta 9
Pregunta
The hands can be a prime indicator of ALS. Split hand syndrome seen in ALS describes the preferential wasting of the [blank_start]thenar[blank_end] muscle group.
Pregunta 10
Pregunta
Primary Lateral Sclerosis differs from Amyotrophic Lateral Sclerosis in that it does NOT show signs of [blank_start]lower[blank_end] motor neuron degeneration
Pregunta 11
Pregunta
Which condition has a better prognosis?
Pregunta 12
Pregunta
There is a strong link between ALS and which type of dementia?
Pregunta 13
Pregunta
Babinski Sign suggests that a patient has experienced [blank_start]upper[blank_end] motor neuron degeneration
Pregunta 14
Pregunta
What are the two most common causes of death in ALS patients?
Respuesta
-
Respiratory failure
-
Pneumonia
-
Cardiac failure
-
Endocarditis
-
Lung cancer
-
Choking from aspiration
Pregunta 15
Pregunta
The pathological hallmark of ALS is the presence of [blank_start]inclusion[blank_end] bodies (abnormal aggregations of protein) in the cytoplasm of motor neurons
Respuesta
-
inclusion
-
subtrusian
-
lewy
-
tau
-
ubiquitin
Pregunta 16
Pregunta
How are reflexes affected by ALS?
Pregunta 17
Pregunta
[blank_start]Kennedy's[blank_end] Disease is an X-linked recessive condition of the motor neurons in the brainstem and spinal cord. Degeneration of these structures leads to weakness and muscle cramps. It is commonly misdiagnosed as ALS.
Pregunta 18
Pregunta
Kennedy's Disease [blank_start]only affects males[blank_end]
Pregunta 19
Pregunta
What is the main treatment for the respiratory failure seen in ALS patients?
Respuesta
-
Invasive ventilation
-
Non-invasive ventilation
Pregunta 20
Pregunta
Which sodium channel antagonist can be given to patients with ALS, prolonging their life by 2-3 months?
[blank_start]Riluzole[blank_end]