Uterine Cancer

Descripción

Endometrial carcinomas
Matthew Coulson
Test por Matthew Coulson, actualizado hace más de 1 año
Matthew Coulson
Creado por Matthew Coulson hace más de 5 años
5
2

Resumen del Recurso

Pregunta 1

Pregunta
Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in [blank_start]post-menopausal[blank_end] women.
Respuesta
  • post-menopausal
  • pre-pubertal
  • pre-menopausal

Pregunta 2

Pregunta
The peak incidence of endometrial carcinoma is [blank_start]50-60 years[blank_end]. It is uncommon for endometrial carcinoma to present in those [blank_start]under 40[blank_end]
Respuesta
  • under 40
  • over 65
  • 50-60 years
  • 30-40 years
  • 70-80 years

Pregunta 3

Pregunta
Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer. HNPCC is also known as [blank_start]Lynch[blank_end] Syndrome
Respuesta
  • Lynch

Pregunta 4

Pregunta
Lynch Syndrome, as well as predisposing the individual to colorectal cancer (HNPCC), also leaves the individual at high risk of which three of the following cancers?
Respuesta
  • Endometrial cancer
  • Breast cancer
  • Ovarian cancer
  • Vulval cancer
  • Lung cancer
  • Oesophageal cancer

Pregunta 5

Pregunta
Which two of the following are Type I Endometrial Carcinomas?
Respuesta
  • Endometrioid
  • Serous
  • Clear Cell
  • Mucinous

Pregunta 6

Pregunta
Which two of the following are Type II Endometrial Carcinomas?
Respuesta
  • Endometrioid
  • Mucinous
  • Serous
  • Clear Cell

Pregunta 7

Pregunta
[blank_start]Type I[blank_end] Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia [blank_start]Type II[blank_end] Endometrial Carcinomas are associated with TP53 mutation
Respuesta
  • Type II
  • Type I

Pregunta 8

Pregunta
A serous endometrial carcinoma is associated with unopposed oestrogen
Respuesta
  • True
  • False

Pregunta 9

Pregunta
Atypical hyperplasia is a precursor to clear cell endometrial carcinoma
Respuesta
  • True
  • False

Pregunta 10

Pregunta
The precursor to endometrioid carcinoma is atypical hyperplasia.
Respuesta
  • True
  • False

Pregunta 11

Pregunta
Mucinous Endometrial Carcinomas are associated with TP53 mutation
Respuesta
  • True
  • False

Pregunta 12

Pregunta
Mucinous Endometrial Carcinomas are associated with unopposed oestrogen.
Respuesta
  • True
  • False

Pregunta 13

Pregunta
Which of the following are associated with Microsatellite Instability?
Respuesta
  • Endometrioid Endometrial Carcinoma
  • Mucinous Endometrial Carcinoma
  • Serous Endometrial Carcinoma
  • Clear Cell Endometrial Carcinoma

Pregunta 14

Pregunta
Which condition is defined as the following? "Germline mutation of DNA mismatch repair genes" [blank_start]Lynch Syndrome[blank_end]
Respuesta
  • Lynch Syndrome

Pregunta 15

Pregunta
Obesity is a highly substantial risk factor for endometrial carcinoma
Respuesta
  • True
  • False

Pregunta 16

Pregunta
Obesity is a risk factor for endometrial carcinoma as fat cells called adipocytes express an enzyme called [blank_start]aromatase[blank_end] which converts ovarian androgens into oestrogens, thus promoting endometrial proliferation.
Respuesta
  • aromatase

Pregunta 17

Pregunta
Lynch Syndrome has an autosomal [blank_start]dominant[blank_end] inheritance pattern
Respuesta
  • dominant

Pregunta 18

Pregunta
One of the characteristic traits of Lynch Syndrome is a lack of Microsatellite Instability
Respuesta
  • True
  • False

Pregunta 19

Pregunta
Type II Endometrial Carcinomas (Serous and Clear Cell) are more aggressive than Type I cancers as they spread along the fallopian tube mucosa allowing extrauterine presentation.
Respuesta
  • True
  • False

Pregunta 20

Pregunta
Which of the following Type II Endometrial Carcinomas is known to spread to the peritoneum early in the disease process?
Respuesta
  • Serous Endometrial Carcinoma
  • Clear Cell Endometrial Carcinoma

Pregunta 21

Pregunta
Endometrioid carcinoma has good prognosis as it is usually confined to the uterus at presentation
Respuesta
  • True
  • False

Pregunta 22

Pregunta
Uterine Leiomyomas are also called Uterine [blank_start]Fibroids[blank_end]
Respuesta
  • Fibroids
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