Pregunta 1
Pregunta
Endometrial polyps are a common cause of dysfunctional uterine bleeding and typically occur in [blank_start]post-menopausal[blank_end] women.
Respuesta
-
post-menopausal
-
pre-pubertal
-
pre-menopausal
Pregunta 2
Pregunta
The peak incidence of endometrial carcinoma is [blank_start]50-60 years[blank_end].
It is uncommon for endometrial carcinoma to present in those [blank_start]under 40[blank_end]
Respuesta
-
under 40
-
over 65
-
50-60 years
-
30-40 years
-
70-80 years
Pregunta 3
Pregunta
Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a hereditary malignant syndrome which leaves the individual highly susceptible to other forms of cancer.
HNPCC is also known as [blank_start]Lynch[blank_end] Syndrome
Pregunta 4
Pregunta
Lynch Syndrome, as well as predisposing the individual to colorectal cancer (HNPCC), also leaves the individual at high risk of which three of the following cancers?
Respuesta
-
Endometrial cancer
-
Breast cancer
-
Ovarian cancer
-
Vulval cancer
-
Lung cancer
-
Oesophageal cancer
Pregunta 5
Pregunta
Which two of the following are Type I Endometrial Carcinomas?
Respuesta
-
Endometrioid
-
Serous
-
Clear Cell
-
Mucinous
Pregunta 6
Pregunta
Which two of the following are Type II Endometrial Carcinomas?
Respuesta
-
Endometrioid
-
Mucinous
-
Serous
-
Clear Cell
Pregunta 7
Pregunta
[blank_start]Type I[blank_end] Endometrial Carcinomas are associated with unopposed Oestrogen and atypical hyperplasia
[blank_start]Type II[blank_end] Endometrial Carcinomas are associated with TP53 mutation
Pregunta 8
Pregunta
A serous endometrial carcinoma is associated with unopposed oestrogen
Pregunta 9
Pregunta
Atypical hyperplasia is a precursor to clear cell endometrial carcinoma
Pregunta 10
Pregunta
The precursor to endometrioid carcinoma is atypical hyperplasia.
Pregunta 11
Pregunta
Mucinous Endometrial Carcinomas are associated with TP53 mutation
Pregunta 12
Pregunta
Mucinous Endometrial Carcinomas are associated with unopposed oestrogen.
Pregunta 13
Pregunta
Which of the following are associated with Microsatellite Instability?
Respuesta
-
Endometrioid Endometrial Carcinoma
-
Mucinous Endometrial Carcinoma
-
Serous Endometrial Carcinoma
-
Clear Cell Endometrial Carcinoma
Pregunta 14
Pregunta
Which condition is defined as the following?
"Germline mutation of DNA mismatch repair genes"
[blank_start]Lynch Syndrome[blank_end]
Pregunta 15
Pregunta
Obesity is a highly substantial risk factor for endometrial carcinoma
Pregunta 16
Pregunta
Obesity is a risk factor for endometrial carcinoma as fat cells called adipocytes express an enzyme called [blank_start]aromatase[blank_end] which converts ovarian androgens into oestrogens, thus promoting endometrial proliferation.
Pregunta 17
Pregunta
Lynch Syndrome has an autosomal [blank_start]dominant[blank_end] inheritance pattern
Pregunta 18
Pregunta
One of the characteristic traits of Lynch Syndrome is a lack of Microsatellite Instability
Pregunta 19
Pregunta
Type II Endometrial Carcinomas (Serous and Clear Cell) are more aggressive than Type I cancers as they spread along the fallopian tube mucosa allowing extrauterine presentation.
Pregunta 20
Pregunta
Which of the following Type II Endometrial Carcinomas is known to spread to the peritoneum early in the disease process?
Pregunta 21
Pregunta
Endometrioid carcinoma has good prognosis as it is usually confined to the uterus at presentation
Pregunta 22
Pregunta
Uterine Leiomyomas are also called Uterine [blank_start]Fibroids[blank_end]