Pregunta 1
Pregunta
There is a decreased absorption of [blank_start]acidic[blank_end] drugs such as phenytoin, aspirin and penicillins in elderly patients due to an increasingly [blank_start]alkaline[blank_end] gastric pH
Respuesta
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alkaline
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acidic
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acidic
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alkaline
Pregunta 2
Pregunta
Elderly people have a [blank_start]higher[blank_end] volume of distribution of lipophilic drugs than the general population.
Pregunta 3
Pregunta
Grapefruit Juice, in theory, causes myalgia in patients who take which of the following medication types?
Respuesta
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Statins
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Antimuscarinics
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Calcium Channel Blockers
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Beta Blockers
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ACE Inhibitors
Pregunta 4
Pregunta
Cranberry juice is known to lower a patient's INR, thus making thromboembolism more likely.
Pregunta 5
Pregunta
The end of a human chromosome, which progressively shortens within each cell replication, is called the [blank_start]telomere[blank_end]
Pregunta 6
Pregunta
In humans, a telomere consists of multiple repeats of which single motif:
Respuesta
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TTAGGG
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AATCCC
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CCGTTT
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GCCAAA
Pregunta 7
Pregunta
Relating to telomeres, the [blank_start]Hayflick[blank_end] limit is the number of times a normal human cell population will divide before cell division stops
Pregunta 8
Pregunta
Sepsis in elderly patients usually presents with [blank_start]a decreased[blank_end] temperature
Pregunta 9
Pregunta
Delirium typically has a [blank_start]fluctuating[blank_end] course
Pregunta 10
Pregunta
[blank_start]Hypoactive[blank_end] delirium has twice the mortality rate of [blank_start]hyperactive[blank_end] delirium
Respuesta
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hyperactive
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hypoactive
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Hypoactive
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hyperactive
Pregunta 11
Pregunta
In terms of the 4AT score:
In terms of Alertness, a patient who has mild sleepiness for <10s after waking then is normal receives which score?
Pregunta 12
Pregunta
In terms of the 4AT score:
A patient whose alertness is judged to be 'clearly abnormal' would receive a score of ...
Pregunta 13
Pregunta
In terms of the 4AT score:
After Alertness, the second part of the 4AT score assesses AMT4, which involves the patient stating their age, DOB, where they are and the current year.
No mistakes warrants a score of [blank_start]0[blank_end]
1 mistake warrants a score of [blank_start]1[blank_end]
2 or more mistakes warrants a score of [blank_start]2[blank_end]
Pregunta 14
Pregunta
In terms of the 4AT score:
After assessing 4AT, the patient has their attention span assessed. In order to do this, the patient is asked to name the months of the year backwards from December.
Achieves 7 months or more correctly = [blank_start]0[blank_end]
Starts but scores <7 months/refuses to start = [blank_start]1[blank_end]
Untestable (too unwell, too drowsy, etc) = [blank_start]2[blank_end]
Pregunta 15
Pregunta
In terms of the 4AT score:
After testing attention, the last parameter which is tested is the presence of an acute or fluctuating course (i.e. evidence of significant change or fluctuation in alertness, cognition, etc)
A fluctuating course warrants a score of [blank_start]4[blank_end]
Pregunta 16
Pregunta
The maximum score a patient can get for the 4AT is
Pregunta 17
Pregunta
In delirious patients, which medication is first line for sedation if it is needed (e.g. if patient is psychotic or refusing to stay in bed)?
[blank_start]Haloperidol[blank_end]
Pregunta 18
Pregunta
For sedation of delirious patients, Haloperidol should be given intramuscularly.
Pregunta 19
Pregunta
Delirium is a risk factor for developing dementia
Pregunta 20
Pregunta
Age related loss of muscle mass and function is called [blank_start]sarcopenia[blank_end]
Pregunta 21
Pregunta
Muscle mass starts to decline as of age [blank_start]30[blank_end]
Pregunta 22
Pregunta
The suggested target for physical activity in the elderly population (65+) is the same as it is for the adult population (18-64)
Pregunta 23
Pregunta
Weekly Physical Activity Guidelines for Adults (18-64) and Elderly (65+):
[blank_start]150[blank_end] minutes of moderate intensity activity
OR
[blank_start]75[blank_end] minutes of vigorous intensity activity
Strength and balance work should also be included at least [blank_start]2[blank_end] times per week
Pregunta 24
Pregunta
Which of the following has been shown to increase muscle function associated with sarcopenia in elderly patients?
Respuesta
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Beta Blockers
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ACE Inhibitors
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Calcium Channel Blockers
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Dopamine Agonists
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Levothyroxine
Pregunta 25
Pregunta
When stepping up a patient from codeine to morphine for analgesia, the following must be considered:
10mg of Codeine is equivalent to [blank_start]1[blank_end]mg of morphine.
Pregunta 26
Pregunta
In order to convert the dosage of MST Morphine to the equivalent dosage of Oramorph, you divide the former by [blank_start]6[blank_end].
For example, a patient on 60mg of MST would take [blank_start]10[blank_end]mg of Oramorph to have the same effect.
Pregunta 27
Pregunta
Smoothest delivery of medicines in palliative care patients is via a continuous subcutaneous infusion using a [blank_start]syringe[blank_end] driver
Pregunta 28
Pregunta
In terms of using Syringe Drivers to administer medications in the elderly, how many different medicines can be mixed together in one syringe?
Pregunta 29
Pregunta
Morphine is [blank_start]two times[blank_end] as potent when given subcutaneously (as opposed to oral administration)
Respuesta
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two times
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three times
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half
Pregunta 30
Pregunta
Arrange the steps of pharmacokinetics in order starting with the point the drug enters the body.
[blank_start]Absorption[blank_end]
[blank_start]Distribution[blank_end]
[blank_start]Metabolism[blank_end]
[blank_start]Excretion[blank_end]
Respuesta
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Absorption
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Metabolism
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Excretion
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Distribution
Pregunta 31
Pregunta
Elderly people typically have a [blank_start]decreased[blank_end] small bowel surface area
Pregunta 32
Pregunta
Protein binding of drugs:
[blank_start]Albumin[blank_end] binds to Acidic Drugs
[blank_start]Alpha-1 Acid Glycoprotein[blank_end] binds to Alkaline Drugs
Pregunta 33
Pregunta
Elderly patients typically have [blank_start]decreased[blank_end] albumin levels and [blank_start]increased[blank_end] alpha-1 acid glycoprotein levels
Respuesta
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increased
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decreased
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decreased
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increased
Pregunta 34
Pregunta
Elderly patients typically have a [blank_start]decreased[blank_end] body water level.
Pregunta 35
Pregunta
Very importantly, the Volume of Distribution of Hydrophilic drugs (lithium, digoxin, etc) in elderly patients is [blank_start]decreased[blank_end].
Pregunta 36
Pregunta
It is generally accepted that higher doses of medications are needed to achieve the same effects in the elderly population.
Pregunta 37
Pregunta
Which of the following minerals interferes with levothyroxine
Pregunta 38
Pregunta
Verapamil (CCB) should never been given with which drug type, for fear of causing symptomatic heart block?
Respuesta
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Beta Blocker
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Statins
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Anticonvulsants
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Thiazide Diuretics