Clinical Immunology Test 2- PMU

Descripción

Medicine Immunology Test sobre Clinical Immunology Test 2- PMU, creado por Med Student el 11/04/2019.
Med Student
Test por Med Student , actualizado hace más de 1 año
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5

Resumen del Recurso

Pregunta 1

Pregunta
The lymphoid inflitration of thyroidea is typical for
Respuesta
  • Hashimoto's Thyroiditis
  • Euthroid struma
  • Hemolytic anemia
  • Tuberculosis

Pregunta 2

Pregunta
Which method is not useful for detection of specific IgE?
Respuesta
  • imumonoenzyme techniques (ELISA. immuno blot)
  • classic reactions (agglutination, precipitation)
  • flowcytometry
  • chemiluminescence

Pregunta 3

Pregunta
I type allergic reactions are
Respuesta
  • immuno-complex
  • cytotoxic
  • IgE mediated
  • cell mediated

Pregunta 4

Pregunta
Monoclonal antibodies connected with diphtheria toxin could be used for
Respuesta
  • tumor diagnosis
  • immunostimulation
  • immunosuppressive therapy
  • immunotherapy for tumors

Pregunta 5

Pregunta
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics a. Multiple sclerosis [blank_start]6[blank_end] b. SLE [blank_start]4[blank_end] c. Myasthenia gravis [blank_start]5[blank_end] d. Pernicious anemia [blank_start]1[blank_end] e. Hashimoto thyoiditis [blank_start]2[blank_end] f. Hemolytic anemia [blank_start]3[blank_end] 1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12 2. autoantibodies against thyroglobuline and thyroid peroxidase 3. antibodies against epitopes of red blood cells 4. antibodies against nucleus antigens 5. antibodies against acetylcholine 6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
Respuesta
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Pregunta 6

Pregunta
Which of the following human tumor antigens are connected with melanoma malignuum?
Respuesta
  • CA 15-3
  • gp 1900
  • MART-1 Melan A
  • gp 120

Pregunta 7

Pregunta
Type II allergic reactions are realized through
Respuesta
  • anaphylaxis
  • complement-mediated cytolysis
  • immune complexes
  • infectious immunity

Pregunta 8

Pregunta
EBV can cause development of
Respuesta
  • hepatoma
  • nasopharyngeal carcinoma
  • the Burkitt lymphoma
  • adenocarcinoma pulmonis

Pregunta 9

Pregunta
Anaphylactic reactions
Respuesta
  • are developed in very short time - 30 min
  • can be followed by inflammatory complication some hours later
  • are result of release of active mediators
  • all answers are correct

Pregunta 10

Pregunta
Autoimmune diseases due to antibodies could be a result of: (mark the wrong answer)
Respuesta
  • generation of antigen-antibody complexes
  • antibody-induced complement mediated cytolysis
  • antibodies that inhibit cell receptor
  • cell-mediated reaction

Pregunta 11

Pregunta
The Bence-Jones protein can be find mostly in
Respuesta
  • urine and serum
  • liquor
  • joint puncture
  • tumor biopsy

Pregunta 12

Pregunta
Immuno - scintigraphy uses monoclonal antibodies against tumor antigens connected with
Respuesta
  • FITC
  • Rodamine
  • Iodine-131, technetium
  • Enzyme

Pregunta 13

Pregunta
What as it we can use as a substrate for detecting of antinuclear antibodies with IFA
Respuesta
  • rat liver
  • rat kidney
  • rat stomach
  • HEp2 cell line

Pregunta 14

Pregunta
Point two diseases where we can use the Mantoux reaction [blank_start]Leprosy[blank_end] [blank_start]Tuberculosis[blank_end]
Respuesta
  • Leprosy
  • Tuberculosis

Pregunta 15

Pregunta
CA-15-3 is a marker for first choice in diagnosis of:
Respuesta
  • Hepatoma
  • Ca glandulae mamme
  • Melanoma malignum
  • Astrocytoma

Pregunta 16

Pregunta
III type allergic reaction is developed through
Respuesta
  • SLE
  • Rheumatoid arthritis
  • Contact dermatitis
  • Acute rheumatism

Pregunta 17

Pregunta
The blocking factors secreted from tumor cells during tumor growth
Respuesta
  • stop cell growth of tumor cells
  • stop the action of Tc-lymphocytes onto tumor cells
  • stop stimulation of tumor specific B-cells
  • are connected with T-lymphocytes and lead to lysis of tumor cells

Pregunta 18

Pregunta
Systemic lupus erythematodes
Respuesta
  • is caused by mutation in dsDNA
  • is an example of T mediated disease
  • is manifested with many symptoms and affect many organs
  • is a result of forming of immune complexes

Pregunta 19

Pregunta
The atopic diseases are developed because:
Respuesta
  • often contacts with allergen
  • they are inheritable
  • they are developed due to immune complexes
  • of IgE

Pregunta 20

Pregunta
We find autoantibodies against cytotoxic antigens of neutrophils (ANCA) mainly in
Respuesta
  • the Goodpasture syndrome
  • amyloidodis
  • granulomatosis of Wegener
  • none of this

Pregunta 21

Pregunta
The Bence-Jones protein is
Respuesta
  • free heavy chains
  • free light κ or λ chains, imperceptible with electrophoresis
  • autoantibodies from IgM class against normal antibodies (IgG) in patients with rheumatoid arthritis
  • fc fragment of complement

Pregunta 22

Pregunta
CEA is increased in
Respuesta
  • nasopharyngeal carcinoma
  • lymphoma Burkitt
  • gastrointestinal tumors
  • smokers

Pregunta 23

Pregunta
The most used techniques for detection of antinuclear antibodies antibodies are
Respuesta
  • direct immmunofluocrescent test
  • indirect immunofluorescent test
  • agglutination
  • neutralization
  • reaction for
  • ELISA

Pregunta 24

Pregunta
How fast is the reaction in cases of type 1 hypersensitivity?
Respuesta
  • after 15-30 minutes
  • after 48 hours

Pregunta 25

Pregunta
The most frequent biological carcinogens are
Respuesta
  • Mycoplasmas
  • Chlamydia
  • DNA- viruses
  • RNA- viruses

Pregunta 26

Pregunta
Connect with arrows allergic diseases with relevant type allergic reaction a. Type I [blank_start]3[blank_end] b. Type II [blank_start]4[blank_end] c. Type III [blank_start]1[blank_end] d. Type IV [blank_start]2[blank_end] 1. serum disease 2. contact dermatitis 3. anaphylaxis 4. hemolytic disease of the newborn
Respuesta
  • 3
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Pregunta 27

Pregunta
Glomerutonephritis and vessel diseases due to antibodies are typical for
Respuesta
  • the Arthus Phenomenon
  • edema angioneuroutic
  • SLE
  • anaemia haemolytica

Pregunta 28

Pregunta
Anti-mitochondrial antibodies are mostly
Respuesta
  • detected in patients with primary biliary cirrhosis
  • detected in patients with rheumatoid arthritis
  • do not harm the organism

Pregunta 29

Pregunta
In case of Ca glandulae prostate is increased the serum levels of
Respuesta
  • PSA (prostate specific antigen)
  • Antibodies against H.pylori
  • Calcitonin
  • Progesterone

Pregunta 30

Pregunta
Auto antibodies against microsomes of thyroid cells can be detected in case of
Respuesta
  • Ca gl. thyroidae
  • Ca renis
  • Pancreatitis
  • Ca pancrei

Pregunta 31

Pregunta
Autoimmune hemolytic anemia in developed mostly via
Respuesta
  • Type I allergic reactions
  • Type II allergic reactions
  • Type III allergic reactions
  • Type IV allergic reactions

Pregunta 32

Pregunta
Rheumatoid factor from the serum of patients with rheumatoid arthritis is
Respuesta
  • IgM reacting with Fc fragment of endogenous IgG
  • IgM reacting wit Fab fragment of IgG
  • IgE reacting with bacterial antigens
  • Acute-phase proteins
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