Transition Block - Pharmacology

Which of the following drugs is not used as secondary prevention for myocardial infarction?

Which of the following drugs is most likely to cause hyperkalaemia?

For Acute treatment of an MI, consider MONA + T: M = [blank_start]Morphine[blank_end] O = [blank_start]Oxygen[blank_end] N = [blank_start]Nitrate[blank_end] A = [blank_start]Aspirin[blank_end] T = [blank_start]Ticagrelor[blank_end]

Omeprazole should be used with caution in patients with renal failure

Km is the concentration at which a drug works at [blank_start]half[blank_end] of its Vmax

Which of the following drugs will not interact pharmacodynamically with the others listed to cause hypotension?

For a drug that exhibits 1st order kinetics administered by IV infusion, a steady state plasma concentration is achieved when the rate of administration equals the half of the rate of elimination

A patient recently started on a new medication has been experiencing constant pains in her muscles. She is an avid grapefruit juice fan. What medication is she taking?

Furosemide is mainly excreted via the [blank_start]kidneys[blank_end]

Before surgery, for how many days should warfarin therapy be stopped?

Treatment of paracetamol overdose:

Both Viagra and isosorbide mononitrate are vasodilators so given in conjunction this would cause syncope

Which of the following pain relief options is suitable for a patient taking Warfarin?

The in vivo effects of paracetamol are similar to those of the [blank_start]selective cyclooxygenase-2 (COX-2)[blank_end] inhibitors.

In a drug which shows first order elimination kinetics, how many half lives does it take for the drug to be fully excreted from the body? [blank_start]5[blank_end] half lives

Cyclizine is a histamine [blank_start]type 1[blank_end] antagonist used as an antiemetic (first line in pregnancy morning sickness)

Allopurinol should not be given in a dose higher than [blank_start]100[blank_end]mg per day