Cell & Muscle Signalling

Descripción

Year 2 Test sobre Cell & Muscle Signalling, creado por gina_evans0312 el 20/10/2013.
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Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace alrededor de 11 años
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Resumen del Recurso

Pregunta 1

Pregunta
What effect does extracellular homeostasis have on intracellular homeostasis?
Respuesta
  • It overrides it
  • It is overridden by it
  • It has no effect

Pregunta 2

Pregunta
What type of messenger is released by extodermal shedding?
Respuesta
  • Membrane bound
  • Direct diffusion
  • Vesicle bound

Pregunta 3

Pregunta
How are cytoplasmic formed chemical messengers released?
Respuesta
  • Lipophillic diffusion through the membrane
  • Dedicated passenger proteins
  • Hydrophillic diffusion through the membrane

Pregunta 4

Pregunta
What Mr can be passed through direct diffusion?
Respuesta
  • Low
  • Moderate
  • High

Pregunta 5

Pregunta
Which part of the myosin in the musce fibre contains the ATPase?
Respuesta
  • Hinge region
  • Light chain
  • Heavy chain

Pregunta 6

Pregunta
What make up the Troponin complex in muscle?
Respuesta
  • Troponin C
  • Troponin I
  • Troponin T
  • Actin
  • Myosin

Pregunta 7

Pregunta
Why is the sarcomere pronounced as a 'cell unit'?
Respuesta
  • Muscles are polynucleatre
  • Sarcomeres are the largest subunit
  • They are the only subunits containing both actin/myosin

Pregunta 8

Pregunta
What muscular receptors are effected by Ach?
Respuesta
  • Nicotinic Ach receptors
  • Adeninic Ach receptors
  • Adrenergic Ach receptors

Pregunta 9

Pregunta
How long is the half life of Ach
Respuesta
  • 1-2 secs
  • 10-20 secs
  • 4-5 secs

Pregunta 10

Pregunta
How many subunits make up Nicotinic Ach Receptors?
Respuesta
  • 5- 2 alpha, a beta a delta and a gamma
  • 5- an alpha, 2 beta, a delta and a gamma
  • 5- an alpha, a beta, 2 delta and a gamma

Pregunta 11

Pregunta
All subunits in Nicotinic Ach Receptors have a transmembrane domain of 4 helices- which one is ampipathic?
Respuesta
  • M1
  • M2
  • M3
  • M4

Pregunta 12

Pregunta
When Ach binds, the subunits twist to replace an amino acid with an inorgaic ion. Name them.
Respuesta
  • Leucine is replaced with Phosphate
  • Tyrosine is replace with Sodium
  • Serine is replace with Chlorine

Pregunta 13

Pregunta
When the impulse enters the muscle cell, what channels are opened in the T-tubule?
Respuesta
  • DHP
  • AHP
  • CHP

Pregunta 14

Pregunta
Once the DHP receptor has been opened, which receptor does it open in the Sarcoplasmic Reticulum?
Respuesta
  • Ryonadine
  • Acetylcholamine
  • Phosphodine

Pregunta 15

Pregunta
What keeps the Ca2+ concentration in the sarcoplasmic reticulum so high?
Respuesta
  • ATP driven Ca2+ pumps
  • Ca2+/Cl- co-transporters
  • Ca2+/Na+ exchange

Pregunta 16

Pregunta
Of the transmembrane helices in DHP, which do which jobs?
Respuesta
  • S4 - voltage sensing S5-6 form pores
  • S5-6 - voltage sensing S4-form pores
  • S2 - voltage sensing S3-4 form pores

Pregunta 17

Pregunta
What allows the DHP receptor to communicate with the Ryonadine receptor?
Respuesta
  • Loops II-III
  • Loops III-IV
  • Loops I-II

Pregunta 18

Pregunta
In the ryonadine receptor, the 6 hydrophobic helices are found in make up how many identical subunits?
Respuesta
  • 4
  • 5
  • 6
  • 7

Pregunta 19

Pregunta
The pore is formed in ryonadine receptors by what?
Respuesta
  • The loops between S9 & S10
  • The loops between S10 & S11
  • The loops between S8 & S9

Pregunta 20

Pregunta
What protein holds the Ca2+ inside the sarcoplasmic reticulum for extra security?
Respuesta
  • Calsequestrin
  • Calcitachin
  • Calcibindin

Pregunta 21

Pregunta
Which subunit of the dihydropyridine receptor contains 4 homologous transmembrane domains?
Respuesta
  • Alpha 1
  • Beta
  • Alpha 2
  • Gamma

Pregunta 22

Pregunta
How many helices make up each one of the four homologous transmembrane domains in the alpha one subunit of Dihydropyridine receptor?
Respuesta
  • 6
  • 4
  • 8
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