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327309
PIP2 Pathway
Description
Year 2 Quiz on PIP2 Pathway, created by gina_evans0312 on 04/11/2013.
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cell signalling and cancer
signalling
year 2
Quiz by
gina_evans0312
, updated more than 1 year ago
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Created by
gina_evans0312
about 11 years ago
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Resource summary
Question 1
Question
Once tyrosine kinase is activated, which protein binds?
Answer
Phospholipase Cgamma
Phospholipase Cdelta
Phospholipase Calpha
Question 2
Question
How does tyrosine kinase activate phospholipase cX?
Answer
No, really, how'd you think? What else could it POSSIBLY BE
Phosphorylation
Question 3
Question
What is the function of Phospholipase Cgamma?
Answer
PIP3 breakdown
PIP2 breakdown
PIP breadown
Question 4
Question
What happens to phospholipase cX when it binds to T.K?
Answer
It is phosphorylated
It's dephosphorylated
Question 5
Question
Name the products of PIP breakdown
Answer
IP3
DAG
No seriously, how many times have we covered this protein family?
Question 6
Question
What subunit allows Phospholipase Cgamma to be recruited to the phosphorylated tyrosine kinase?
Answer
SH3
SH2
SH4
Question 7
Question
Most of the phospholipase cgamma's effects are the same as phospholipase Cbeta, which one is different?
Answer
PKC activation causes the activation of Na+/H+ pumps
PKC activation causes the activation of Na+/K+ pumps
PKC activation causes the activation of Na+/Cl- pumps
Question 8
Question
What is the effect of the membrane pump activation?
Answer
Cell becomes more alkaline
Cell becomes more acidic
Cell prepares for mitosis
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