412799
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
|
Creado por gina_evans0312
hace alrededor de 11 años
|
|
Pregunta 1
Pregunta
What is the main difference between apoptosis and necrosis?
Respuesta
-
In necrosis release of cell contents is controlled In apoptosis it's not
-
In apoptosis release of cell contents is controlled In necrosis it's not
Pregunta 2
Pregunta
What protein condenses during apoptosis
Respuesta
-
Chromatin
-
Actin
-
Myosin
Pregunta 3
Pregunta
What form are caspases usually found in?
Respuesta
-
Inactive, with their DED domain tails intact
-
Active, with their DED domain tails intact
-
Inactive, with their DED domain tails removed
-
Active, with their DED domain tails removed
Pregunta 4
Pregunta
What is required for caspase activation?
Respuesta
-
Addition of a DED domain tail
-
Removal of the DED domain tail
Pregunta 5
Pregunta
What are the roles of the 2 main caspases?
Respuesta
-
3 is the initation 8 does most damage
-
8 is the initiator 3 does most damage
Pregunta 6
Pregunta
Which of the following are survival/protector proteins that inhibit caspase activation?
Respuesta
-
BAX, BAD, PUMA
-
Bci-2, Mcl1, A1
Pregunta 7
Pregunta
What is required for ligand acitvated apoptosis?
Respuesta
-
For the receptors to contain DED domains
-
For the receptors to be bound to caspases
-
For the receptors to be expressed only in certain areas of the cell membrane
Pregunta 8
Pregunta
What protein inhibits the activation of apoptic receptors?
Respuesta
-
Flp
-
Flr
-
Fld
Pregunta 9
Pregunta
Name an apoptic receptor
Respuesta
-
Fas
-
Far
-
Fam
Pregunta 10
Pregunta
How does the receptor activate caspase 8?
Respuesta
-
By recruiting it and cleaving off the DED domain
-
By recruiting it and adding a DED domain
Pregunta 11
Pregunta
Name the two methods caspase 8 uses to destroy the cell
Respuesta
-
Activation of Caspase 3
-
Deactivation of Caspase 3
-
Damage to mitochondria, which releases Cyt. C
Pregunta 12
Pregunta
What does mitochondrial damage do to Casp 9?
Respuesta
-
Activates it
-
Deactivates it
Pregunta 13
Pregunta
What happens when essential growth factors are withdrawn from the cell?
Respuesta
-
PI3K cannot activate
-
PKB cannot activate
-
Casp 8 cannot activate
Pregunta 14
Pregunta
How does PKB inhibit apoptosis?
Respuesta
-
Releases Bad from Blc-2
-
Releases Blc2 from Bad
Pregunta 15
Pregunta
Identify methods which cells can use to evade apoptosis
Respuesta
-
Decreased Fas receptor expression
-
Inc Blc2 & decrease bax/bad expression
-
Loss of Casp 8
-
Increased Flp expression
-
Soluble fas to causes apoptosis in t-cells
-
Large amounts of Fas ligand produced to kill t-cells
¿Quieres crear tus propios Tests gratis con GoConqr? Más información.