444041
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace casi 11 años
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Pregunta 1
Pregunta
The complimentation test is used to find out if mutations are allelic or non allelic
Respuesta
- True
- False
Pregunta 2
Pregunta
In what circumstances will a Complimentation Test give a false result?
Respuesta
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When the mutation is recessive
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When the mutation is dominant
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When the mutated gene is part of a complex
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Where proteins form multimers
Pregunta 3
Pregunta
Genotypes M1 & M2 are bred together, and a Wild Type result is obtained- are the mutations allelic
Respuesta
-
No- as the presentation of a wild type phenotypes shows there is at least one dominant wild type allele for each gene
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Yes- The two mutations on the same allele are able to compliment each other sufficiently to produce a wild type phenotype
Pregunta 4
Pregunta
If M3 and M2 are bred together and they present as M2, what does this tell us about the mutation's location?
Respuesta
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They are on the same allele- there is no dominant wild type allele to mask their activity
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They are on separate alleles, but M2 has a far greater effect than previously thought
Pregunta 5
Pregunta
According to the above table, which mutations are allelic
Respuesta
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M9 & M4
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M8 & M6
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M2
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All of the above
Pregunta 6
Pregunta
A Complimentation Test can be fooled if the mutant protein can form a functioning heterodimer with the wild type protein
Respuesta
- True
- False
Pregunta 7
Pregunta
One gene is said to be epistatic to another if...
Respuesta
-
The presence of a double mutant exhibits the phenotype of the mutant gene
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The presence of the wild type masks the phenotype of the mutant gene
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A genes expression causes a change in the expression of another gene further down the pathway
Pregunta 8
Pregunta
Where are epistatic genes usually found in substrate dependent pathways?
Respuesta
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Upstream
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Downstream
Pregunta 9
Pregunta
A substrate dependent pathway is a series of positive and negative regulators that act on one another of the final product
Respuesta
- True
- False
Pregunta 10
Respuesta
- True
- False
Pregunta 11
Pregunta
Why should null alleles be used for epistatic analysis (i.e how to find out the order of gene function in a pathway)
Respuesta
-
The masking of alleles downstream becomes obvious
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They are easier to make than hypomorphic alleles
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They can be used for both Substrate Dependent and Switch pathways
Pregunta 12
Pregunta
How do we identify that the pathway effected by the (epistatic) mutation is a Switch Regulatory pathway?
Respuesta
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If the mutation prevents the production of the final product
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If the phenotype of a double mutant is different to the phenotype of either single mutant
Pregunta 13
Pregunta
The Rif1 & Rif2 strains are both causes lengthened telomeres, as shown in the diagram. Based on the Rif1/Rif2 double mutation, which of the two availible pathways (shown) is likely to be the one used?
Image:
Rif1 (image/png)
Respuesta
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Pathway A
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Pathway B
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