445668
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
Which of the following can cause double strand breaks in the DNA?
Respuesta
-
Ionising radiation
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Meiosis
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Chemicals
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DNA replication errors
Pregunta 2
Pregunta
What are Chromosome Fragile Sites?
Respuesta
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Sites where double strand breaks are likely to occur
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Sites that can be easily split accidentally by protein machinery
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Sites that are likely to warp during heat shock
Pregunta 3
Pregunta
Chromosome fragile sites are thought to be caused by difficulties during meiosis
Respuesta
- True
- False
Pregunta 4
Pregunta
What does NHEJ stand for?
Respuesta
-
Non-homologous end joining
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Non-homologous editing joints
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Non-heterodimeric end joints
Pregunta 5
Pregunta
What are the requirements for NHEJ?
Respuesta
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Double strand breaks
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Single strand breaks
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T-T lesions
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DNA ligase 4
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DNA ligase 2
Pregunta 6
Pregunta
The repair process of NHEJ will join any 2 free ends together, regardless of homology
Respuesta
- True
- False
Pregunta 7
Pregunta
An error in NHEJ can lead to translocation between which chromosomes, forming what type of chromosome fusion?
Respuesta
-
Philadelphia chromosome
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Inverted chromosome
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8 &12
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9 & 22
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13 & 21
Pregunta 8
Pregunta
The repair process of Homologous Recombination relies on what?
Respuesta
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That the damaged sequence in the sister chromatid is intact
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That the damaged sequence in the homologous chromosome is intact
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That the damaged sequence in the other allele is intact
Pregunta 9
Pregunta
What is required for an error in Homologous Recombination?
Respuesta
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A faulty alignment of the two chromosomes
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A faulty alignment of the two chromatids
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Due to inversions
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Due to translocations
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Due to repeats
Pregunta 10
Respuesta
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NHEJ
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Homologous Recombination
Pregunta 11
Pregunta
A fault in Homologus Recombination can lead to alleles being lost
Respuesta
- True
- False
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