447465
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace casi 11 años
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Pregunta 1
Pregunta
Why is human african tropanomosis so common?
Respuesta
-
Most drugs are outdated
-
Most drugs have severe side effects
-
Most drugs are incredibly expensive
-
Most drugs cannot be used on the immunocompromised
Pregunta 2
Pregunta
The cause of Human African Tropanomosis is a virus known as Tropanosome
Respuesta
- True
- False
Pregunta 3
Pregunta
Tropanosomes contain 1 mitochondria that depends on what for energy?
Respuesta
-
Glycerol-3-Dehydrogenase
-
Succinate Dehydrogenase
-
NADH Dehydrogenase
-
Malate Dehydrogenase
Pregunta 4
Pregunta
The enzyme that tropanosomes rely on allows glycolysis to continue indefinitely
Respuesta
- True
- False
Pregunta 5
Pregunta
What other components make up the tropanonsome's mitochondria?
Respuesta
-
Alternative Oxidase
-
Quinol
-
Cytochrome C
-
Cytochrome BC1 complex
Pregunta 6
Pregunta
How does Alternative Oxidase get its energy source?
Respuesta
-
Glucose in the blood plasma
-
Glucose in the infected red blood cell
-
Glucose from other blood proteins
Pregunta 7
Pregunta
Cryptosporidium Parvum can only become fatal to the immunocompromised
Respuesta
- True
- False
Pregunta 8
Respuesta
-
Cryptosporidium parvum cysts
-
Cryptosporidium parvum oocysts
-
Cryptosporidium parvum oocytes
Pregunta 9
Pregunta
Which of the following are characteristic of Alternative Oxidase?
Respuesta
-
Membrane bound
-
Cytoplasmic
-
Reduces O2 to H2O
-
Reduces O2 to H2O2
-
No absorption about 340nm
Pregunta 10
Pregunta
Alt. Ox. is a 34kDa monomer
Respuesta
- True
- False
Pregunta 11
Pregunta
Why does Alt. Ox. not absorb above 340nm?
Respuesta
-
It contains no Cyt's or Fe-S
-
It contains no chromosomes
-
It contains no Cty's or Flavins
Pregunta 12
Pregunta
To activate, Alt. Ox must form a dimer
Respuesta
- True
- False
Pregunta 13
Pregunta
What is particular about Rubreythrin?
Respuesta
-
It is the olden protein yet sequenced - 4 billion years old
-
It's the smallest protein yet sequenced - just 40 aa long
-
It's the largest protein yet sequenced - 400,000 kDa
Pregunta 14
Pregunta
Only 6 aa in Alt. Ox have been conserved, relating it to other di-iron proteins
Respuesta
- True
- False
Pregunta 15
Pregunta
The conserved sequence of Alt. Ox. codes for amino acids holding what?
Respuesta
-
Iron
-
Magnesium
-
Copper
-
Sodium
Pregunta 16
Pregunta
Which of the following list characteristics of Alt. Oxidase?
Respuesta
-
Sits horizontally in the membrane
-
Sits vertically in the membrane
-
Made of 2 chains, almost entirely of alpha helices
-
Made of 3 chains, almost entirely of alpha helices
-
Made of 2 chains, almost entirely of beta sheets
Pregunta 17
Pregunta
2 Alpha helices dock Alt. Ox in the membrane
Respuesta
- True
- False
Pregunta 18
Pregunta
How does the substrate get to Alt. Ox's active site?
Respuesta
-
Through a hydrophobic cavity
-
It is 'caught' by alpha helices extending into the cytoplasm
-
It uses membrane phospholipids which move through it
Pregunta 19
Pregunta
The following shows the core of Alt. Oxidase- what's contained in it?
Image:
Alt._Ox._Core (image/png)
Respuesta
-
2 Fe atoms
-
2 Cu atoms
-
Linked by hydroxyl groups
-
Linked by amide groups
-
From 4 leucine residues
-
From 4 glutamine residues
-
And 2 Histadine &1 Tyrosine residues
Pregunta 20
Pregunta
The Histadine/Tyrosine residues can be used to inhibit Alt. Ox
Respuesta
- True
- False
Pregunta 21
Pregunta
To travel through the channel and reach the active site, inhibitors must be...
Respuesta
-
Hydrophobic
-
Hydrophillic
Pregunta 22
Pregunta
Different co-ordinations of the aa in the Alt. Ox core can alter the function of it
Respuesta
- True
- False
Pregunta 23
Pregunta
Alt. Ox. is a terminal respiratory chain oxidase
Respuesta
- True
- False
Pregunta 24
Pregunta
Where is Alt. Ox found, in infected humans?
Respuesta
-
Between Complexes 1 & 2
-
Between complexes 2 & 3
-
Between complexes 3 & 4
Pregunta 25
Pregunta
Alternative Ox is used as a stress protein in pathogens, and an oxygen scavenger in plants
Respuesta
- True
- False
Pregunta 26
Pregunta
Which of the following use Alt. Ox?
Respuesta
-
American/Asian Skunk Cabbage
-
Dead Horse Arum
-
Sacred Lotus
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