Atherogenesis

Descripción

(Lipid Deficiencies) Year 2 Test sobre Atherogenesis, creado por gina_evans0312 el 15/02/2014.
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Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312 hace casi 11 años
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Resumen del Recurso

Pregunta 1

Pregunta
What is an Atheroma?
Respuesta
  • Artifical thickening of arterial cell walls that excludes a thick lipid mix
  • Artificial coarsening of arterial cell walls that shed bacteria into the bloodstram
  • Bacterial biofilm forming over the cell wall

Pregunta 2

Pregunta
What causes the Endothelial Dysfunction that begins atheroma growth?
Respuesta
  • Cigarette smoke
  • Excess LDL's
  • Bacterial infection
  • Autoimmune disorders
  • Diabetes

Pregunta 3

Pregunta
What happens to epithelial cells during Endothelial Dysfunction?
Respuesta
  • They become lipoprotein soluble and lose cell repellant quality
  • They become lipoprotein inoluble and gain cell repellant quality
  • They become lipoprotein soluble and gain cell repellant quality

Pregunta 4

Pregunta
VCAM- A monocyte adhesion molecule that allows them to enter the vascular wall
Respuesta
  • True
  • False

Pregunta 5

Pregunta
Once monocytes convert to macrophages in tissue, what do they produce?
Respuesta
  • ROS
  • Acids
  • Bases

Pregunta 6

Pregunta
During Lipid Deposition, lipids can easily enter the damaged endothelial walls
Respuesta
  • True
  • False

Pregunta 7

Pregunta
What happens to LDL's once they enter the tissue
Respuesta
  • They're oxidied by macrophages
  • They're reduced by macrophages

Pregunta 8

Pregunta
LDLs are so easily reduced due to low tissue antioxidants
Respuesta
  • True
  • False

Pregunta 9

Pregunta
What happens when Macrophages take up too many LDL's?
Respuesta
  • They become dying Foam cells
  • They become dying Plasma cells
  • They become dying Mast cels

Pregunta 10

Pregunta
As the macrophages die, the release lipid pools
Respuesta
  • True
  • False

Pregunta 11

Pregunta
Name the two main components of the plaque?
Respuesta
  • Foam cells
  • Lipid pools
  • LDLs
  • Mast cells
  • Plasma cells

Pregunta 12

Pregunta
Vascular cells form a fibrous cap over the developing clot
Respuesta
  • True
  • False

Pregunta 13

Pregunta
What, potentially can happen to the fibrous plaque coat?
Respuesta
  • It calcifies and fissures at the edges
  • It becomes layered with t-cells and macrophages
  • Bacteria stick to it and invade tissues

Pregunta 14

Pregunta
Name the effect of arterial plaques
Respuesta
  • Blood flow decreases
  • Blood pressure rises
  • Blood flow increases
  • Plaque forces artery to widen
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