Pregunta | Respuesta |
What is Autoimmunity | A Sustained adaptive immune response to a self antigen which causes tissue damage |
What are some examples of Autoimmune diseases | Ankylosing Spondylitis - arthritis in the spine Type 1 Diabetes Rhuematoid Arthritis SLE - Systemic Lupus Erythematosis Graves Disease |
Explain autoimmunity | The body produces self antigens to protect us from foreign antigens - autoimmunity is when the immune system is unable to differentiate self from foreign. This is a chronic disease as our bodies never stop producing self antigens. |
What is the difference between Hypersensitivity Reactions and Autoimmunity Reactions | Autoimmune reactions involve self antigens not foreign antigens. There isnt a type 1 reaction - like in hypersensitivity. |
Explain Type 2 Autoimmunity | Same as Type 2 Hypersensitivity; Autoantigen binds to cell Complement dependent lysis Antibody dependent cellular cytotoxicity |
Name diseases of Type 2 Autoimmunity | Hasimotos Disease - hypothyroid Graves Disease - Hyperthyroid |
Explain Type 3 Autoimmunity | Auto-antigen is free Immune complexes form Complexes deposit in blood or tissue Complement activated Inflammation at site of deposit Enzymes and chemicals released Tissue damage caused |
Name diseases of Type 3 Autoimmunity | RA SLE |
How do we treat Autoimmune Diseases | Glucocorticoids Prednisone System specific therapy Symptom relief |
Describe Immunodeficiency | Partial or Total loss of function of one or more components of the immune system. Inherited or Genetic |
What is Primary Immunodeficiency | Inherited, Congenital or Genetic failure of the immune system. Congenital Hypoglobulinemia - B cells Thymic Aplasia - Low T cells DiGeorges Syndrome - Low Mature T cells |
What is Secondary Immunodeficiency | Acquired loss of immune function from specific causes. Infections - HIV Malnutrition Cancer |
What is the treatment for Immunodeficiencies | Blood Transfusions - replacing antibodies with gammaglobulins Bone Marrow or Thymus transplants |
¿Quieres crear tus propias Fichas gratiscon GoConqr? Más información.