The Fed Metabolism

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(Metabolic States) Year 2 Fichas sobre The Fed Metabolism, creado por gina_evans0312 el 28/02/2014.
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Creado por gina_evans0312 hace casi 11 años
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Resumen del Recurso

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Liver- Glucose Transporter (And why) GLUT2- So that glucose only enters when glucose is high (say after a meal) and glycogen must be made
Liver- Glucose Made into glycogen/pyruvate
Liver- Pyruvate Made into F.A's through Acetyl CoA
Liver- Acetyl CoA Used to make TAGs or enters the TCA cycle
Liver- Glycerol Used to make TAG's
Liver- TAG's Leave the liver as VLDLs to provide sustenance for other cells
Muscle- Glucose Transporter 4, so glucose is available at all time
Muscle- Glucose Used to make glycogen, or converted to pyruvate
Muscle- Pyruvate Used for the TCA cycle (nothing else)
Muscle- Amino Acids Used to make protein (to build muscle) or Acetyl CoA for the TCA cycle
Muscle- LPL For the breakdown of VLDLs/Chylomicrons for Acetyl CoA
Adipose Tissue- Glucose Receptor 4- affected most by insulin, bc fat generation depends on state of body
Adipose Tissue- Glucose Made into Glycerol-3-phosphate for fat generation, or into pyruvate
Adipose Tissue- Pyruvate For acetyl CoA, for TAG generation and the TCA cycle
Adipose Tissue- LPL Grabs F.As from VLDLs/Chylomicrons to make TAGs
Brain Tissue- Glucose Transporters 1 & 3- most sensitive to glucose since the brain can't use anything else
Brain Tissue- Glucose Acetyl CoA for the TCA cycle. No exceptions that they've taught us
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