Neissaria Family

Pregunta	Respuesta
N. gonorrheae- Gram Staining	Gram +ve cocci pairs
N. gonorrheae- Culture media	Chocolate agar- needs CO2
N. gonorrheae- Oxidase Test	+ve
N. gonorrheae- Infection Characteristics	Many pus cells, as bacteria can live inside neutraphils
N. gonorrheae- Infection Type	Urethritis
N. meningiditis- Gram Staining	Gram +ve cocci pairs (everything's the same as N. gonorrheae)
N. meningiditis- Initial Infection Location	Nasopharynx, allows it to reach the brain and blood
N. meningiditis- Infection Type	Meningitis, septicemia
Miningococcal Septicemia- Infection Characteristics	A non-blanching rash
Miningococcal Septicemia- Source	Humans (only reservoir)
Miningococcal Septicemia- Transmission	Close contact
Miningococcal Septicemia- Host Immunity	Usually requires an immunocompromised host
Miningococcal Septicemia- Movement through Body (Normal)	Nasopharynx-blood-CSF
Miningococcal Septicemia- Movement Through Body (Possible)	Through Cribiform Plate in room of mouth, directly through olfactory nerves
Miningococcal Virulence Factors- Pilus	Enable it to penetrate through mucus
Miningococcal Virulence Factors Outer membrane proteins-	Target specific epithelial receptors allow easy binding to cells
Miningococcal Virulence Factors- Capsule	Evade immune responses - i.e. hides c3b compliment proteins during opsonisation
Miningococcal Virulence Factors- Sialic Acid	Found in host cells, allows evasion of immune response
Miningococcal Virulence Factors- IgA Protease	Breaks down binding Igs
Miningococcal Virulence Factors- Compliment Inhibitory Factor	Kinda obvious...
Miningococcal Virulence Factors- Neutrophils	Can actively divide inside them, by resisting ROS attacks and using them as a hiding place

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	Creado por gina_evans0312 hace más de 10 años