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5281950
Adaptive Immune Response
Descripción
Microbiology
Sin etiquetas
immune
adaptive
microbiology
Mapa Mental por
Mohd Amirul Faiz Zulkifli
, actualizado hace más de 1 año
Más
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Creado por
Mohd Amirul Faiz Zulkifli
hace más de 8 años
37
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0
Resumen del Recurso
Adaptive Immune Response
It is specific
Immune components are activated only after infection start
Response magnitude is higher in the second and subsequent encounter
Immunological memory is stored
Lymphoid organs
Primary
Production sites of immune cells
Maturation sites for immune cells in the absence of antigen
Secondary
Maturation sites for antigen-driven immune cells
Lymphocyte
T cells
Mature in thymus
B cells
Mature in bone marrow
Antigen- independence
Have surface markers or receptors
Bind to antigens
Bind to receptors on other cells
Transmit and receive messages
Receptor molecules
Major histocompatibility complex (MHS)
Classes
Class 1
Expressed on all nucleated cells
Class 2
Antigen-presenting cells
Class 3
Protein associated with the complement system
Cluster of differentiation (CD)
CD4
Binds to MHS class 2
CD8
Binds to MHS class 1
Antigen-specific receptors
Mature T and B cells
Carry one specific type of receptors called clones
To eliminate lymphocytes that recognize self-antigens
T-cell receptors
Supported by CD4 and CD8
Immunoglobulins (Ig) or antibodies in B cells
IgG, IgA, IgM, IgE, IgD
T-cell Response
T helper cell
Activate other cells
Memory T cell
Store immunological memory
Regulatory T cells
Prevent excessive inflammation and autoimmunity
Cytotoxic T cells
Attack infected, cancerous and foreign cells
B cells
Memory B cells
Store immunological memory
Regulatory B cells
Prevent excessive inflammation and autoimmunity
Plasma cells
Launch antibodies
Neutralisation
Opsonisation
Agglutination
Antitoxin action
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