Contrave
naltrexone/ bupropion hydrochloride
Adult Dosing .
Dosage forms: 8 ER/90 ER
obesity, long-term tx
[2 tabs PO bid]
Start: 1 tab PO qam x1wk, then 1 tab PO bid x1wk, then 2 tabs PO qam and 1 tab PO qpm x1wk; Max: 4 tabs/day; Info: D/C if wt loss <5% after 12wk on max dose; do not cut/crush/chew tab; avoid admin. w/ high fat meal
Cardiac
Neutral:
Red
Migraines/
Headaches
Qsymia:
Phentermine/Topiramate
Nota:
Qsymia
phentermine hydrochloride/ topiramate
Adult Dosing .
Dosage forms: 3.75/23 ER,7.5/46 ER,11.25/69 ER,15/92 ER
obesity, long-term tx
[7.5 mg/46 mg or 15 mg/92 mg PO qam]
Start: 3.75 mg/23 mg PO qam x14 days, then incr. to 7.5 mg/46 mg PO qam; Max: 15 mg/92 mg/day; Info: if wt loss <3% after 12wk, consider D/C or incr. dose to 11.25 mg/69 mg PO qam x14 days, then 15 mg/92 mg PO qam; D/C if wt loss <5% after 12wk on max dose; taper max dose to qod >1wk to D/C
Restricted Distribution in US [1-888-998-4887 or http://www.QsymiaREMS.com for more info]
Overeating
Phentermine
Nota:
phentermine hydrochloride obesity, short-term tx
[15-37.5 mg PO qam]Max: 37.5 mg/day; Info: give before or 1-2h after breakfast; may divide dose bid; tabs may be split, but do not cut/crush/chew caps; D/C when tolerance occurs; taper dose gradually to D/C if prolonged, high dose use
Binge Eating
Disorder
Nota:
Binge eating disorder (BED) is an eating disorder characterized by recurrent episodes of eating large quantities of food (often very quickly and to the point of discomfort); a feeling of a loss of control during the binge; experiencing shame, distress or guilt afterwards; and not regularly using unhealthy compensatory measures (e.g., purging) to counter the binge eating. Binge eating disorder is a severe, life-threatening and treatable eating disorder. Common aspects of BED include functional impairment, suicide risk and a high frequency of co-occurring psychiatric disorders.
Vyvanse
Nota:
Vyvanse
lisdexamfetamine
Adult Dosing .
Dosage forms: 10,20,30,40,50,60,70
ADHD
[30-70 mg PO qam]
Start: 30 mg PO qam, may incr. by 10-20 mg/day qwk; Max: 70 mg/day; Info: duration 10-14h; use lowest effective dose; periodically reassess need for tx; taper dose gradually to D/C if prolonged, high dose use; may open cap
Lorcaserin
Nota:
Qsymia
phentermine hydrochloride/ topiramate
Adult Dosing .
Dosage forms: 3.75/23 ER,7.5/46 ER,11.25/69 ER,15/92 ER
obesity, long-term tx
[7.5 mg/46 mg or 15 mg/92 mg PO qam]
Start: 3.75 mg/23 mg PO qam x14 days, then incr. to 7.5 mg/46 mg PO qam; Max: 15 mg/92 mg/day; Info: if wt loss <3% after 12wk, consider D/C or incr. dose to 11.25 mg/69 mg PO qam x14 days, then 15 mg/92 mg PO qam; D/C if wt loss <5% after 12wk on max dose; taper max dose to qod >1wk to D/C
Restricted Distribution in US [1-888-998-4887 or http://www.QsymiaREMS.com for more info]
Cardiac
Neutral:
Red
ADHD
Evekeo
Nota:
Evekeo
amphetamine
Adult Dosing .
Dosage forms: 5,10
ADHD
[5-40 mg/day PO divided qd-tid]
Start: 5 mg PO qam or bid, incr. by 5 mg/day qwk; Info: give divided doses at 4-6h intervals; doses >40 mg/day rarely more effective; taper dose gradually to D/C if prolonged, high dose useTreating attention deficit hyperactivity disorder (ADHD). It is also used to treat a type of sleep disorder (narcolepsy). It is also used on short-term basis (a few weeks) in combination with other treatments to treat obesity. It may also be used for other conditions as determined by your doctor.Evekeo is a central nervous system stimulant. Exactly how it works is not known. It affects certain chemicals in the brain, which may help to improve attention span and behavior.
Vyvanse
Nota:
Vyvanse
lisdexamfetamine
Adult Dosing .
Dosage forms: 10,20,30,40,50,60,70
ADHD
[30-70 mg PO qam]
Start: 30 mg PO qam, may incr. by 10-20 mg/day qwk; Max: 70 mg/day; Info: duration 10-14h; use lowest effective dose; periodically reassess need for tx; taper dose gradually to D/C if prolonged, high dose use; may open cap
Diabetes
AVOID:
BELVIQ
Saxenda/
Victoza
Nota:
Saxenda
liraglutide
Adult Dosing .
Dosage forms: SC
obesity, long-term tx
[3 mg SC qd]
Start: 0.6 mg SC qd x1wk, then may incr. dose by 0.6 mg/day qwk; Max: 3 mg/day; Info: retitrate from 0.6 mg SC qd if tx interrupted for >3 daysSaxenda (liraglutide) is similar to a hormone that occurs naturally in the body and helps control blood sugar, insulin levels, and digestion.Saxenda is an injectable prescription medicine that may help some obese adults or overweight adults who also have weight related medical problems lose weight and keep the weight off. It is used together with diet and exercise.Saxenda is not a weight-loss medicine or appetite suppressant.