Question | Answer |
Why are antibiotics, like penicillins, and cephalosporins, not effective against fungi? | Penicillins, and cephalosporins act on the synthesis of peptidoglycan in the bacterial cell wall, and not chitin in the fungal cell wall. |
Name the polysaccharides of fungal cell wall. | Chitin (made up of N-acetylglucosamine) & β- glycan (of D-glucose) |
What is the mechanism of action of antifungal caspofungin? | It acts on the β-glycan polysaccharide in the fungal cell wall. |
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