Glycogenesis

Question	Answer
What factors inhibit and stimulate Glycogen Synthase (form alpha 1-4 bonds)?	Stimulate: Glucose-6-Phosphate, Adrenaline, Insulin. Inhibit: Glucagon, Ca
What role does UDP-Glucose play? and how do we form it?	UDP-Glucose is the handle used to form alpha 1-4 bonds. We form it through Uridine (UTP) and Glucose-1 Phosphate combining (through enzyme UDP-Glucose Pyrophosphoryllase) forming UDP-Glucose and 2Pi.
What is Glycogenesis?	Formation of Glycogen
How do we form Alpha 1-4 bonds?	UDP-Glucose (Uridine+2Pi) acts as the glue to form the bonds. UDP-Glucose is formed through the breakdown of UTP-Glucose by the enzyme UDP-Glucose Phosphorylase.
How do we form Alpha 1-6 bonds?	We form 1-6 bonds by Glycogen Synthase which activates a branching enzyme which causes the linear glucose chain to snap and reattach forming a branch.
What role does Insulin play?	When Insulin levels are high (High Glucose) we form glucose through Glycogenesis. When Insulin is low (Low Glucose) we form glucose through Glycogenolysis.

Resource summary

	Created by Mark Arsenal almost 13 years ago