GLUT Transporters

Question	Answer
GLUT1- Role	Constituative, responsible for basal uptake
GLUT1- Location	Almost every tissue
GLUT1- Glucose Affinity	2.5-8mM
GLUT2- Role	Prevents entry of glucose into certain cells to preserve it for when necessary
GLUT2- Location	Liver and pancreatic B cells
GLUT2- Glucose Affinity	Low, at 15-20mM, but very high uptake in this range
GLUT2- Role in Liver	Allows glucose entry for storage when blood glucose levels are high enough
GLUT2- Role in Pancreas	When glucose is high enough, enters beta cells and signals insulin release
GLUT3- Role	Compliment GLUT1 uptake in highly active tissues
GLUT3- Location	Brain
GLUT4- Role	Basal insulin uptake (but is most effected by insulin)
GLUT4- Location	Skeletal muscle
GLUT4- Glucose Affinity	5mM, but this changes with insulin secretion
GLUT5- Role	Fructose transporter
GLUT5- Location	Found in the small intestine

Resource summary

	Created by gina_evans0312 almost 11 years ago